Association of Helicobacter pylori positivity with the symptoms in patients with hyperemesis gravidarum

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dc.contributor.authorGungoren, Arif
dc.contributor.authorBayramoglu, Neslihan
dc.contributor.authorDuran, Nizami
dc.contributor.authorKurul, Mehmet
dc.date.accessioned2024-09-18T20:54:29Z
dc.date.available2024-09-18T20:54:29Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractTo investigate the relationship between Helicobacter pylori (Hp) positivity and the severity of symptoms of nausea and vomiting in patients diagnosed with hyperemesis gravidarum (HG). Prospective controlled. Ninety patients with the diagnosis of HG below the 20th week gestation, who had no additional disease and 50 pregnant women with no complaints were enrolled in the study. According to the severity of symptoms, the patients were divided into three groups as group I, II and III (mild, moderate and severe, respectively). The Rhode's scoring system was used to determine the severity of HG symptoms. HpIgG and IgM levels were determined in the blood samples and Hp DNA positivity with PCR was investigated in the saliva. In accordance with the Rhode's scoring system, 15.5 % of the pregnant women had mild, 58.9 % had moderate, and 25.6 % had severe symptoms (group I, II and III, respectively). HpIgG was determined as positive in 78.6, 84.9 and 82.6 % in groups I, II and III, respectively. HpIgM positivity was determined as 26.1 % only in group III (p = 0.847). HpDNA was determined as 7.2, 3.8, and 91.3 % in group I, II, and III, respectively (p < 0.01). While HpIgG was positive in 60 %, HpDNA was found to be positive in 2 % and HpIgM was found to be negative in all the pregnant women in the control group. A positive relationship between the symptoms of HG and Hp positivity was determined using PCR.en_US
dc.identifier.doi10.1007/s00404-013-2869-x
dc.identifier.endpage1283en_US
dc.identifier.issn0932-0067
dc.identifier.issn1432-0711
dc.identifier.issue6en_US
dc.identifier.pmid23736829en_US
dc.identifier.scopus2-s2.0-84889088466en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1279en_US
dc.identifier.urihttps://doi.org/10.1007/s00404-013-2869-x
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11825
dc.identifier.volume288en_US
dc.identifier.wosWOS:000326884700018en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofArchives of Gynecology and Obstetricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPregnancyen_US
dc.subjectNauseaen_US
dc.subjectVomitingen_US
dc.subjectHyperemesis gravidarumen_US
dc.subjectHelicobacter pylorien_US
dc.titleAssociation of Helicobacter pylori positivity with the symptoms in patients with hyperemesis gravidarumen_US
dc.typeArticleen_US

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