Subclinical left ventricular dysfunction in multiple sclerosis

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dc.authoridDUMAN, Taskin/0000-0002-6552-4193
dc.contributor.authorAkgul, Ferit
dc.contributor.authorMclek, Ismet
dc.contributor.authorDuman, Taskin
dc.contributor.authorSeyfeli, Ergun
dc.contributor.authorSeydaliyeva, Tunzale
dc.contributor.authorYalcin, Fatih
dc.date.accessioned2024-09-18T20:33:01Z
dc.date.available2024-09-18T20:33:01Z
dc.date.issued2006
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjectives: To investigate the left (LV) and right ventricular (RV) function in multiple sclerosis (MS) using standard echocardiography and Doppler tissue imaging (DTI). Materials and methods: A total of 41 patients with definite MS and 32 healthy controls were included in the study. Results: LV end-systolic dimension was increased and LV ejection fraction was decreased in MS patients compared with controls (P < 0.05). LV end-diastolic dimension was increased in MS patients, however, did not reach significance. Among DTI parameters, mitral annular peak early diastolic velocity to peak late diastolic velocity ratio (Em/Am) was decreased in MS patients, but not reach statistical significance. No significant differences in tricuspid annular Em/Am ratio was found between MS patients and controls. A statistically significant increase of DTI derived LV myocardial performance index was found in MS patients as compared with controls. RV myocardial performance index showed a tendency to be increased in MS patients, however, did not reach significance. Conclusions: These findings suggest subclinical LV dysfunction and preserved RV function in patients with MS.en_US
dc.identifier.doi10.1111/j.1600-0404.2006.00662.x
dc.identifier.endpage118en_US
dc.identifier.issn0001-6314
dc.identifier.issue2en_US
dc.identifier.pmid16867034en_US
dc.identifier.scopus2-s2.0-33745827432en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage114en_US
dc.identifier.urihttps://doi.org/10.1111/j.1600-0404.2006.00662.x
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11263
dc.identifier.volume114en_US
dc.identifier.wosWOS:000238881200007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBlackwell Publishingen_US
dc.relation.ispartofActa Neurologica Scandinavicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectmultiple sclerosisen_US
dc.subjectventricular functionen_US
dc.subjecttissue doppleren_US
dc.titleSubclinical left ventricular dysfunction in multiple sclerosisen_US
dc.typeArticleen_US

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