The Evaluation of HBV-DNA Levels In Patients who Had Lost Hbsag After Recovery From Hepatitis B Virus Infection

dc.contributor.authorMotor, Vicdan Koksaldi
dc.contributor.authorCelikbas, Aysel Kocagsul
dc.contributor.authorBaykam, Nurcan
dc.contributor.authorGok, Sebnem Eren
dc.contributor.authorDokuzoguz, Basak
dc.date.accessioned2024-09-18T20:04:35Z
dc.date.available2024-09-18T20:04:35Z
dc.date.issued2012
dc.departmentHatay Mustafa Kemal Ãœniversitesien_US
dc.description.abstractObjective: The risk of transmitting hepatitis B virus has been reported to continue in the blood of people with loss of HBsAg after recovery from hepatitis B virus infection. The aim of the present study was to investigate the hepatitis B virus DNA in patients with loss HBsAg after recovery from hepatitis B virus infection by using polymerase chain reaction. Materials and Methods: Total 57 cases were evaluated. Hepatitis B virus DNA was detected in 19 (43.2%) of 44 patients with loss of HBsAg after acute hepatitis B virus infection, and in 2 (15.4%) of 13 cases who had natural immunity with positive antiHBs. Results: Infectivity continued in 21 (36.8%) cases. Hepatitis B virus DNA levels were detected between 4.6 x102 with 1x105 genome / mL in these serum samples. Conclusion: In our study, hepatitis B virus DNA can positive in patients with loss of HBsAg after hepatitis B virus infection have been shown. For this reason, antiHBc screening more reliable than HBsAg was thought in the selection of blood donors. It was thought that hepatitis B virus DNA testing with polymerase chain reaction is appropriate in serum and tissues of donors with positive hepatitis B virus serology in the organ transplantation practices.en_US
dc.identifier.doi10.4274/Vhd.54264
dc.identifier.endpage51en_US
dc.identifier.issn1307-9441
dc.identifier.issn2147-2939
dc.identifier.issue2en_US
dc.identifier.startpage47en_US
dc.identifier.urihttps://doi.org/10.4274/Vhd.54264
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8262
dc.identifier.volume18en_US
dc.identifier.wosWOS:000217194500002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofViral Hepatit Dergisi-Viral Hepatitis Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBlood donorsen_US
dc.subjecthepatitis Ben_US
dc.subjectpolymerase chain reactionen_US
dc.titleThe Evaluation of HBV-DNA Levels In Patients who Had Lost Hbsag After Recovery From Hepatitis B Virus Infectionen_US
dc.typeArticleen_US

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