Factors affecting long-term renal functions after partial vs radical nephrectomy for clinical T1 renal masses: A Multicentre Study of the Urooncology Association, Turkey

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dc.authoridGulsen, Murat/0000-0001-5371-0960
dc.authoridCetin, Serhat/0000-0001-5450-5168
dc.authoridGokalp, Fatih/0000-0003-3099-3317
dc.contributor.authorIzol, Volkan
dc.contributor.authorGokalp, Fatih
dc.contributor.authorSozen, Sinan
dc.contributor.authorOzden, Ender
dc.contributor.authorBayazit, Yildirim
dc.contributor.authorMuezzinoglu, Talha
dc.contributor.authorKara, Onder
dc.date.accessioned2024-09-18T21:05:13Z
dc.date.available2024-09-18T21:05:13Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPurpose To compare the functional outcomes of patients who underwent partial (PN) or radical nephrectomy (RN) for clinical T1 (cT1) renal tumours using the Kidney Cancer Database of the Urooncology Association, Turkey. Methods We retrospectively reviewed 1004 patients who underwent PN and RN for cT1 renal tumours at multiple academic tertiary centres between 2000 and 2018. Patients with preoperative end-stage chronic kidney disease and/or metastatic disease were excluded. Results There were 452 patients in the PN group and 552 patients in the RN group. The median follow-ups were 74.9 and 83.7 months in RN and PN cohort. The eGFR was significantly reduced in both groups on postoperative day 1 (PN = 13.7 vs RN = 19.1 mL/min/1.73 m(2): P < .001). In the PN group, eGFR showed a tendency to recover according to a quadratic pattern and reached preoperative levels in the first and third years (95.6 +/- 28.8 mL/min/1.73 m(2) and 96.9 +/- 28.9 mL/min/1.73 m(2), respectively), with no significant difference between the eGFRs in the 1st and 3rd years (P = .710). To define groups at risk, different cut-off values for the GFR were considered. Among patients with a baseline GFR < 90, the RN cohort had significantly lower eGFRs in the first and third years than the PN cohort (P = .02). Logistic regression showed that comorbidities, coronary artery disease, diabetes and hypertension had no adverse impacts on the changes in the eGFR (P = .60, P = .13, and P = .13, respectively). Conclusion For the treatment of stage T1 kidney tumours, open or laparoscopic partial nephrectomy has the benefit to preserve renal function.en_US
dc.identifier.doi10.1111/ijcp.13960
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.issue5en_US
dc.identifier.pmid33394541en_US
dc.identifier.scopus2-s2.0-85099757749en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1111/ijcp.13960
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13456
dc.identifier.volume75en_US
dc.identifier.wosWOS:000610440700001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Hindawien_US
dc.relation.ispartofInternational Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNephron-Sparing Surgeryen_US
dc.subjectChronic Kidney-Diseaseen_US
dc.subjectCell Carcinomaen_US
dc.subjectTumorsen_US
dc.subjectBenefiten_US
dc.titleFactors affecting long-term renal functions after partial vs radical nephrectomy for clinical T1 renal masses: A Multicentre Study of the Urooncology Association, Turkeyen_US
dc.typeArticleen_US

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