Oxidative stress biomarkers of exposure to deltamethrin in rainbow trout fry (oncorhynchus mykiss)

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Küçük Resim

Tarih

2011

Dergi Başlığı

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Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Deltamethrin (DM) is a widely used pesticide based on pyrethroids, and is reported to be extremely toxic to fish species. We investigated the effect of DM concentrations (0.010, 0.0125 and 0.0250 ?g/L) on antioxidants in rainbow trout, Oncorhynchus mykiss, using standard laboratory conditions. 24 h exposure caused whole body induction of various antioxidant enzymes and nonenzymatic antioxidants. Results showed that DM significantly (p< 0.05) increased malondialdehyde (MDA) levels. Catalase (CAT) activity decreased in all experimental groups. Glutathione (GSH) was significantly (p<0.05) increased in the group with DM concentration of 0.0250 ?g/L DM for 24 h. The activity of glutathione peroxidase (GSH-Px) was found to be statistical significantly (p<0.05) decreased in all other experimental groups except the 0.010 ?g/L DM treated group. The parameters studied in this investigation can also be used as biomarkers of exposure to DM. It is suggested that appropriate ecotoxicological risk assessments should be made wherever DM is proposed for use in pest control activities. © by PSP.

Açıklama

Anahtar Kelimeler

Antioxidant system, Deltamethrin, Oxidative stress, Pesticide, Rainbow trout

Kaynak

Fresenius Environmental Bulletin

WoS Q Değeri

Scopus Q Değeri

N/A

Cilt

20

Sayı

8

Künye