Determination of selected antibiotics in farmed fish species using LC-MS/MS

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dc.authoridYipel, Mustafa/0000-0002-6390-9313
dc.authoridTekeli, Ibrahim Ozan/0000-0002-6845-2279
dc.contributor.authorYipel, Mustafa
dc.contributor.authorKurekci, Cemil
dc.contributor.authorTekeli, Ibrahim O.
dc.contributor.authorMetli, Murat
dc.contributor.authorSakin, Fatih
dc.date.accessioned2024-09-18T20:02:35Z
dc.date.available2024-09-18T20:02:35Z
dc.date.issued2017
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe aim of the study was to monitor the occurrence of 37 antibiotics from different classes including fluoroquinolone, tetracycline, macrolide, sulphonamide, penicillin, amphenicol and cephalosporin in three different farmed fish species (n=75; rainbow trout, see bass, gilthead see bream) from five cities in Turkey. A method for LC-MS/MS was optimized and validated to assess these antibiotics. As a result, 25 samples showed contamination with at least one antibiotic residue. The most detected antibiotics were norfloxacin (NOR) (18.7%), marbofloxacin (MAR) (12%), tetracycline (TC) (10.7), danofloxacin (DAN) (9.3%), oxytetracycline (OTC) (9.3%), tilmicosin (TLM) (8%) and enrofloxacin (ENR) (6.7%). A total of 17.3% of samples examined were found to be contaminated with residues exceeding the maximum residue limits (MRLs). The results indicate that antibiotics are frequently used in aquaculture production without the lack of knowledge. This study also revealed that the consumption of farmed fish could produce a public health concern as the level of residues for some antibiotics was much higher than MRLs.en_US
dc.description.sponsorshipMustafa Kemal University [BAP-10501]en_US
dc.description.sponsorshipThe authors are indebted to Adem SARIGOZ (Food Analysis Laboratory, Hatay) for technical help on the LC-MS/MS and to Prof. Dr. Errol HASSAN (University of Queensland, Australia) for valuable comments. This work was financially supported by Scientific Research Projects Coordination of Mustafa Kemal University (BAP-10501).en_US
dc.identifier.doi10.1111/are.13209
dc.identifier.endpage3836en_US
dc.identifier.issn1355-557X
dc.identifier.issn1365-2109
dc.identifier.issue7en_US
dc.identifier.scopus2-s2.0-84995446659en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage3829en_US
dc.identifier.urihttps://doi.org/10.1111/are.13209
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7893
dc.identifier.volume48en_US
dc.identifier.wosWOS:000403357900045en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAquaculture Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectaquacultureen_US
dc.subjectfishen_US
dc.subjectantibioticen_US
dc.subjectresidueen_US
dc.subjectLC-MSen_US
dc.subjectMSen_US
dc.titleDetermination of selected antibiotics in farmed fish species using LC-MS/MSen_US
dc.typeArticleen_US

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