Plasminogen activator inhibitor-1 4G/5G polymorphism and dyslipidemia with branch retinal artery occlusion in a young lady

dc.authorscopusid56150894400
dc.authorscopusid36082430700
dc.authorscopusid57190752693
dc.contributor.authorKurtul, Bengi Ece
dc.contributor.authorElbeyli, Ahmet
dc.contributor.authorOzcan, Sait Coskun
dc.date.accessioned2024-09-19T15:45:21Z
dc.date.available2024-09-19T15:45:21Z
dc.date.issued2020
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBranch retinal artery occlusion (BRAO) leads obstruction of blood flow in the distribution of the affected vessel giving rise to ischemia and reorganization of the retinal layers. It is a very rare diagnosis and the etiological risk factors of BRAO are not clean in the young population. Various hypercoagulable states leading to thrombosis appeared to be more responsible. Here, the authors present an interesting case of a 25-year-old female patient with BRAO accompanying with plasminogen activator inhibitor-1(PAI-1) 4G/5G gene polymorphism and dyslipidemia together, for the first time. There was a history of sudden painless blurred vision in her right eye 3 months ago. Her visual acuity was 20/20 in both eyes at the admittion. Fundus photo, red-free photo, optical coherence tomography images of 3 months ago revealed BRAO in the right eye. Fundus exam and images taken at the 3th month confirmed the recovery of retinal edema. Attenuation of inferotemporal retinal artery still mildly appeared. Applied confrontation fields showed a visual field defect corresponding with affected area. Ophthalmologists are advised to be aware of the importance of PAI-1 4G / 5G gene polymorphism and dyslipidemia conditions besides the other genetic mutations and thrombophilic markers regarding BRAO in young patients. © 2020 Wolters Kluwer Medknow Publications. All rights reserved.en_US
dc.identifier.doi10.4103/ojo.OJO_266_2019
dc.identifier.endpage154en_US
dc.identifier.issn0974-620X
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85096227379en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage152en_US
dc.identifier.urihttps://doi.org/10.4103/ojo.OJO_266_2019
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14610
dc.identifier.volume13en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofOman Journal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBranch occlusionen_US
dc.subjectdyslipidemiaen_US
dc.subjectplasminogen activator inhibitoren_US
dc.subjectpolymorphismen_US
dc.subjectretinal arteryen_US
dc.titlePlasminogen activator inhibitor-1 4G/5G polymorphism and dyslipidemia with branch retinal artery occlusion in a young ladyen_US
dc.typeArticleen_US

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