Effects of Long-Term Boron Administrations on High-Energy Diet-Induced Obesity in Rabbits: NMR-Based Metabonomic Evaluation

Basit Öğe Kaydı
dc.authoridBasoglu, Abdullah/0000-0002-5745-3073
dc.contributor.authorBasoglu, Abdullah
dc.contributor.authorBaspinar, Nuri
dc.contributor.authorOzturk, Aliye Sagkan
dc.contributor.authorAkalin, Pinar Peker
dc.date.accessioned2024-09-18T20:52:49Z
dc.date.available2024-09-18T20:52:49Z
dc.date.issued2011
dc.departmentHatay Mustafa Kemal Ãœniversitesien_US
dc.description.abstractThe aim of this study is to provide insight into boron metabolism and to identify metabolic pathways which may explain the presumed increased susceptibility of livers. Boron was administrated in rabbits at three different doses and 96 h intervals for 7 months. Metabolomic profile based on NMR analysis was performed. The most pronounced findings were significant changes in alanine, methionine, pyruvate and creatine. Boron seems to be effective in the prevention of obesity and fatty liver. Metabolic end-points obtained by NMR can be easily assessed and interpreted alone or in. combination each other and with classical biochemical parameters for better understanding obesity and boron and liver metabolism.en_US
dc.description.sponsorshipEuropean Community [FP6-2004-026164 2006-2009]; Turkish National Boron Research Institute, Coordinating Offices of Selcuk; Mustafa Kemal Universitiesen_US
dc.description.sponsorshipThis study was done at Selcuk University in Turkey. NMR analysis was performed at Wageningen University NMR Centre in The Netherlands. This study was supported by the European Community activity Large-Scale Facility Wageningen NMR Center (FP6-2004-026164 2006-2009), Turkish National Boron Research Institute and Scientific Research Projects (BAP) Coordinating Offices of Selcuk and Mustafa Kemal Universities.en_US
dc.identifier.endpage1515en_US
dc.identifier.issn1680-5593
dc.identifier.issn1993-601X
dc.identifier.issue12en_US
dc.identifier.startpage1512en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11422
dc.identifier.volume10en_US
dc.identifier.wosWOS:000298090300004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherMedwell Onlineen_US
dc.relation.ispartofJournal of Animal and Veterinary Advancesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectObesityen_US
dc.subjectfatty liveren_US
dc.subjectboronen_US
dc.subjectNMRen_US
dc.subjectmethionineen_US
dc.subjectmetabolismen_US
dc.subjectcreativeen_US
dc.titleEffects of Long-Term Boron Administrations on High-Energy Diet-Induced Obesity in Rabbits: NMR-Based Metabonomic Evaluationen_US
dc.typeArticleen_US

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