Plateletcrit and red cell-distribution width are independent predictors of the slow coronary flow phenomenon

Basit Öğe Kaydı
dc.authoridKiran, Sibel/0000-0002-4191-113X
dc.authoridBuyukuysal, Mustafa Cagatay/0000-0001-9810-5633
dc.contributor.authorAkpinar, Ibrahim
dc.contributor.authorSayin, Muhammet Rasit
dc.contributor.authorGursoy, Yusuf Cemil
dc.contributor.authorAktop, Ziyaeddin
dc.contributor.authorKarabag, Turgut
dc.contributor.authorKucuk, Emrah
dc.contributor.authorSen, Nihat
dc.date.accessioned2024-09-18T20:54:18Z
dc.date.available2024-09-18T20:54:18Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground and purpose: Endothelial dysfunction may play a role in the pathogenesis of the slow coronary flow (SCF) phenomenon. A detailed examination of blood cellular components has not been performed for this condition. We investigated the relationship between SCF and whole blood cell counts. Method: Records of 17,315 patients who underwent coronary angiography between January 2006 and December 2012 were evaluated retrospectively. A total of 146 patients with SCF were compared with 148 patients with normal coronary arteries according to demographic data, complete blood count, and biochemical parameters. Results: The following parameters were significantly higher in SCF patients than in patients with normal coronary arteries: percentage of smokers (36.3% vs. 25%, p = 0.036), body mass index (26.69 +/- 2.84 vs. 26.07 +/- 3.15, p = 0.049), white blood cells (WBCs) (7.52 +/- 1.43 x 10(3) mm(-3) vs. 7.01 +/- 1.42 x 10(3) mm(-3), p = 0.002), red cell distribution width (RDW) (13.68 +/- 1.42% vs. 13.15 +/- 1.13%, p < 0.001), platelets (250.29 +/- 50.96 x 10(3) mm(-3) vs. 226.10 +/- 38.02 x 10(3) mm(-3), p < 0.001), plateletcrit (PCT) (0.214 +/- 0.40% vs. 0.184 +/- 0.29%, p < 0.001), mean platelet volume (8.63 +/- 1.10 fL vs. 8.22 +/- 0.83 fL, p < 0.001), platelet distribution width (PDW) (16.58 +/- 0.76% vs. 16.45 +/- 0.57%, p = 0.028), and neutrophils (4.44 +/- 1.25 x 10(3) mm(-3) vs. 4.12 +/- 1.24 x 10(3) mm(-3), p = 0.029). Positive PCT values [odds ratio (OR), 4.165; 95% confidence interval (CI), 2.493-6.959; p < 0.001) and RDW (OR, 1.304; 95% Cl, 1.034-1.645; p = 0.025) were independent predictors of SCF. Conclusion: Although within the normal range, the increased numbers of WBCs and neutrophils in patients with SCF suggest that SCF may be a subclinical inflammatory condition. Furthermore, increased RDW and PDW in SCF patients may cause microvascular blood flow resistance due to impaired cell deformability. The PCT provides reliable data regarding total platelet mass and may be a useful predictor of SCF. (C) 2013 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.jjcc.2013.07.010
dc.identifier.endpage118en_US
dc.identifier.issn0914-5087
dc.identifier.issn1876-4738
dc.identifier.issue1-2en_US
dc.identifier.pmid24012331en_US
dc.identifier.scopus2-s2.0-84893779680en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage112en_US
dc.identifier.urihttps://doi.org/10.1016/j.jjcc.2013.07.010
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11729
dc.identifier.volume63en_US
dc.identifier.wosWOS:000331424100021en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofJournal of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPlateletcriten_US
dc.subjectRed cell distributionen_US
dc.subjectSlow coronary flowen_US
dc.titlePlateletcrit and red cell-distribution width are independent predictors of the slow coronary flow phenomenonen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Tam Metin / Full Text
Boyut:
870.11 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu