Evaluation of mean platelet volume in patients with type 2 diabetes mellitus and blood glucose regulation: a marker for atherosclerosis?

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dc.authoridSumbul, Ahmet Taner/0000-0002-5573-906X
dc.authoridDokuyucu, Recep/0000-0001-7881-8871
dc.authoridUstun, Ihsan/0000-0002-5848-1586
dc.authoridSefil, Fatih/0000-0001-5534-7448
dc.authoridDokuyucu, Recep/0000-0001-6837-3477
dc.contributor.authorUlutas, Kemal Turker
dc.contributor.authorDokuyucu, Recep
dc.contributor.authorSefil, Fatih
dc.contributor.authorYengil, Erhan
dc.contributor.authorSumbul, Ahmet Taner
dc.contributor.authorRizaoglu, Hatice
dc.contributor.authorUstun, Ihsan
dc.date.accessioned2024-09-18T20:32:59Z
dc.date.available2024-09-18T20:32:59Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: Platelets have an important role in atherosclerosis and arterial thrombosis. Cardiovascular complication prevalence of type 2 diabetes mellitus (type 2 DM) may be associated with glycosylated hemoglobin (HbA(1c)) and mean platelet volume (MPV). The aim of the study was to investigate if platelets were activated in diabetes and its associated vascular complications by measuring the MPV in the diabetics compared to the non-diabetics, and to determine the correlation of MPV with fasting serum glucose (FSG), HbA(1c) and duration of diabetes in the diabetic patients, respectively. Materials and Methods: The study carried out in 65 patients with type 2 DM and 40 non-diabetic subjects. In addition to non-diabetic patients, all diabetic patients were divided into two groups according to their HbA(1c) levels: group A consisted of patients with HbA(1c) levels <= 7% and group B consisted of patients with HbA(1c) levels >7%. Results: MPV was significantly higher in Group B as compared to both non-diabetics and Group A. MPV had a high positive correlation with HbA(1c) and FSG, as with diabetes duration. It is found that MPV was increased in type 2 DM. Conclusion: Our findings suggested an association between MPV and HbA(1c). Therefore, MPV would be a beneficial prognostic marker of cardio-vascular complications in patients with type 2 DM.en_US
dc.identifier.endpage961en_US
dc.identifier.issn1940-5901
dc.identifier.issue4en_US
dc.identifier.pmid24955167en_US
dc.identifier.scopus2-s2.0-84900431845en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage955en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11246
dc.identifier.volume7en_US
dc.identifier.wosWOS:000336740600020en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherE-Century Publishing Corpen_US
dc.relation.ispartofInternational Journal of Clinical and Experimental Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMPVen_US
dc.subjectatherosclerosisen_US
dc.subjectglucose regulationen_US
dc.subjectdiabetes durationen_US
dc.titleEvaluation of mean platelet volume in patients with type 2 diabetes mellitus and blood glucose regulation: a marker for atherosclerosis?en_US
dc.typeArticleen_US

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