Evaluation of Lymphocyte Subgroups in Children With Down Syndrome

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dc.authoridBala, Keziban Asli/0000-0001-8755-7714
dc.contributor.authorYilmaz, Cahide
dc.contributor.authorDogan, Murat
dc.contributor.authorBasarslan, Fatmagul
dc.contributor.authorYilmaz, Nebi
dc.contributor.authorYuca, Sevil
dc.contributor.authorBulan, Keziban
dc.contributor.authorKaya, Avni
dc.date.accessioned2024-09-18T20:15:21Z
dc.date.available2024-09-18T20:15:21Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractIn this study, lymphocyte subgroups including blood CD3, CD4, CD8, CD4/CD8, CD19, and CD16.56 values were analyzed in children with Down syndrome (DS). The study includes 85 children with DS, followed at Department of Pediatrics, Faculty of Medicine, Yuzuncu Yil University and 64 healthy age-matched control participants. Blood CD3, CD4, CD8, CD4/CD8, CD19, and CD16.56 values were examined in both the groups. Significantly decreased blood CD3, CD4, and CD19 values were found in the study group (P < .05) when compared with the control group. In conclusion, we would like to emphasize that blood CD3, CD4, and CD19 levels were found to be decreased in children with DS. Based on these finding, we think that these decreased lymphocyte subgroups might be responsible for increased susceptibility to infections in children with DS.en_US
dc.identifier.doi10.1177/1076029613511521
dc.identifier.endpage549en_US
dc.identifier.issn1076-0296
dc.identifier.issn1938-2723
dc.identifier.issue6en_US
dc.identifier.pmid24243939en_US
dc.identifier.scopus2-s2.0-84937835925en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage546en_US
dc.identifier.urihttps://doi.org/10.1177/1076029613511521
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9581
dc.identifier.volume21en_US
dc.identifier.wosWOS:000358581300007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofClinical and Applied Thrombosis-Hemostasisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDown syndromeen_US
dc.subjectlymphocyte subgroupsen_US
dc.subjectCDen_US
dc.titleEvaluation of Lymphocyte Subgroups in Children With Down Syndromeen_US
dc.typeArticleen_US

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