Iron intoxication at children
[ N/A ]
Date
2005
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Access Rights
info:eu-repo/semantics/closedAccess
Abstract
In iron intoxication, ingestion of more than >60 mg/kg alimantery iron, early onset of the symptoms, hyperglycemia (>150 mg/dl), leukocytosis (>15,000 mm3) and determining iron pills at plain graphies of abdomen are signs for severe toxicity and need for chelation therapy. Decontamination of gastrointestinal system (gastric lavage/whole bowel irrigation), infusion of desferrioxamine (15 mg/kg/h) and aggressive management of shock and multiorgan failure are effective. Shock, coagulopathy, severe metabolic acidosis and acute liver failure are signs of poor prognosis. We wanted to discuss clinical picture, diagnosis and treatment of iron intoxication which is frequent in childhood and sometimes a cause for mortality.
Description
Keywords
deferoxamine, iron, blood clotting disorder, chelation, human, hyperglycemia, iron overload, leukocytosis, liver failure, metabolic acidosis, mortality, prognosis, review, shock, stomach lavage
Journal or Series
SENDROM
WoS Q Value
Scopus Q Value
N/A
Volume
17
Issue
7
