The prognostic value of serum albumin levels on admission in patients with acute ST-segment elevation myocardial infarction undergoing a primary percutaneous coronary intervention

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dc.authoridERKOL, AYHAN/0000-0002-9481-048X
dc.authoridAKGUN, Taylan/0000-0002-5395-2027
dc.contributor.authorOduncu, Vecih
dc.contributor.authorErkol, Ayhan
dc.contributor.authorKarabay, Can Y.
dc.contributor.authorKurt, Mustafa
dc.contributor.authorAkgun, Taylan
dc.contributor.authorBulut, Mustafa
dc.contributor.authorPala, Selcuk
dc.date.accessioned2024-09-18T19:52:33Z
dc.date.available2024-09-18T19:52:33Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjectives Hypoalbuminemia is associated with a poor prognosis in patients with end-stage renal disease, chronic ischemic heart disease, heart failure (HF), and stroke. We aimed to investigate its prognostic value in patients with acute ST-segment elevation myocardial infarction (STEMI) treated by a primary percutaneous coronary intervention (p-PCI). Materials and methods We retrospectively enrolled 1706 patients with STEMI treated by p-PCI. We prospectively followed up the patients for a median duration of 40 months. Results On admission, hypoalbuminemia (< 3.5 g/dl) was present in 519 (30.4%) patients. The incidence of final TIMI grade 3 flow (84 vs. 91.4%, P < 0.001) was lower in the patients with hypoalbuminemia. In-hospital mortality (9.4 vs. 2%), HF (20.2 vs. 8.6%), and major bleeding (6 vs. 2.5%) rates were significantly higher in patients with hypoalbuminemia. However, in-hospital stroke and reinfarction rates were similar in both groups. At long-term follow-up (median duration: 42 months), all-cause mortality (23.3 vs. 8.4%, P < 0.001), reinfarction (11.6 vs. 7.7%, P= 0.013), stroke (2.6 vs. 1.1%, P = 0.031), and advanced HF (13.3 vs. 6.1%, P < 0.001) rates were significantly higher in patients with hypoalbuminemia. In the Cox proportional hazard model, hypoalbuminemia was determined as an independent predictor of long-term mortality [hazard ratio 2.98, 95% confidence interval 1.35-6.58, P = 0.007) and development of advanced HF (hazard ratio 2.96, 95% confidence interval 1.44-6.08, P = 0.003). Conclusion Hypoalbuminemia on admission is a strong independent predictor for long-term mortality and development of advanced HF in patients with STEMI undergoing p-PCI. Coron Artery Dis 24: 88-94 (C) 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins.en_US
dc.identifier.doi10.1097/MCA.0b013e32835c46fd
dc.identifier.endpage94en_US
dc.identifier.issn0954-6928
dc.identifier.issn1473-5830
dc.identifier.issue2en_US
dc.identifier.pmid23249632en_US
dc.identifier.scopus2-s2.0-84873407790en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage88en_US
dc.identifier.urihttps://doi.org/10.1097/MCA.0b013e32835c46fd
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7514
dc.identifier.volume24en_US
dc.identifier.wosWOS:000314347700002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofCoronary Artery Diseaseen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectalbuminen_US
dc.subjectheart failureen_US
dc.subjectmyocardial infarctionen_US
dc.subjectprimary angioplastyen_US
dc.subjectprognosisen_US
dc.titleThe prognostic value of serum albumin levels on admission in patients with acute ST-segment elevation myocardial infarction undergoing a primary percutaneous coronary interventionen_US
dc.typeArticleen_US

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