DECREASED HEART RATE VARIABILITY IN SICKLE CELL ANEMIA AS EFFECT OF PULMONARY ARTERIAL HYPERTENSION

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dc.authoridFettser, Denis/0000-0002-4143-8899
dc.authoridBatyraliev, Talantbek/0000-0003-4251-0327
dc.contributor.authorAkgul, F.
dc.contributor.authorBatyraliev, T. A.
dc.contributor.authorFettser, D., V
dc.contributor.authorSeyfeli, E.
dc.contributor.authorArystan, A. G.
dc.contributor.authorSeydaliyeva, T.
dc.contributor.authorGali, E.
dc.date.accessioned2024-09-18T20:57:00Z
dc.date.available2024-09-18T20:57:00Z
dc.date.issued2019
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractDecreased heart rate variability (HRV) is associated with increased mortality risk in various diseases. The objective of this investigation: to study HRV in patients with sickle cell anemia (SCA) and to assess the effect of pulmonary arterial hypertension (PAH) on HRV in these patients. Materials and methods. HRV registration and Doppler echocardiographic assessment of systolic pulmonary arterial pressure (PAP) was carried out in 61 stable patients with SCA and 24 healthy subjects. Results. Low frequency power (LFP) and high frequency power (HFP) were decreased in SCA patients compared to healthy subjects. Among SCA patients, PAH patients had lower LFP and HFP than patients without PAH. In SCA patients, systolic PAP showed significant negative correlation with LFP and HFP. Conclusion. HRV is significantly decreased in SCA patients, especially in those with PAH. HRV may be particularly useful in early detection of PAH patients who may have worse prognosis and higher mortality risk.en_US
dc.identifier.doi10.18087/cardio.2019.4.10237
dc.identifier.endpage44en_US
dc.identifier.issn0022-9040
dc.identifier.issue4en_US
dc.identifier.pmid31002038en_US
dc.identifier.scopus2-s2.0-85064869896en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage39en_US
dc.identifier.urihttps://doi.org/10.18087/cardio.2019.4.10237
dc.identifier.urihttps://hdl.handle.net/20.500.12483/12236
dc.identifier.volume59en_US
dc.identifier.wosWOS:000474853700006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoruen_US
dc.publisherRussian Heart Failure Socen_US
dc.relation.ispartofKardiologiyaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSickle cell anemiaen_US
dc.subjectpulmonary hypertensionen_US
dc.subjectheart rate variabilityen_US
dc.titleDECREASED HEART RATE VARIABILITY IN SICKLE CELL ANEMIA AS EFFECT OF PULMONARY ARTERIAL HYPERTENSIONen_US
dc.typeArticleen_US

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