Amotivational syndrome: less known and diagnosed as a clinical

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dc.contributor.authorAri, Mustafa
dc.contributor.authorSahpolat, Musa
dc.contributor.authorKokacya, M. Hanifi
dc.contributor.authorCopoglu, U. Sertan
dc.date.accessioned2024-09-18T19:54:17Z
dc.date.available2024-09-18T19:54:17Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Ãœniversitesien_US
dc.description.abstractAmotivational syndrome (AS) is a disorder that includes apathy, callousness and antisocial behavior in chronic cannabis users. Some of these effects may generally be seen in other central nervous system depressants as well. Therefore, to make these effects specific for this syndrome is still debated. AS is usually seen among men during puberty. In different studies, the incidence of AS in regular cannabis users has been reported as between 16 to 21%. Although the causes accused in pathophysiology is still controversial, cannabis is the most commonly accused factor in the etiology. In neurobiology of the disease, noradrenergic and dopaminergic systems containing changes in limbic road have been blamed. The diagnosis is based on subjective complaints, and scored by clinical signs and Apathy Evaluation Scale (AES). There are very few experimental data available in treatment of AS, and clinical experience is very limited. By PubMed searching the keywords of 'amotivational syndrome, cannabis and amotivational syndrome, cannabis and motivation' from 1960 to December 2013, the published studies examining the relationship between marijuana and AS have been reviewed. We have reached 536 articles, of which 76 include direct relationship with AS, by the end of this search. Non-English articles were excluded from the study.en_US
dc.identifier.doi10.5455/jmood.20140907115343
dc.identifier.endpage35en_US
dc.identifier.issn2146-1473
dc.identifier.issn2146-2380
dc.identifier.issue1en_US
dc.identifier.startpage31en_US
dc.identifier.urihttps://doi.org/10.5455/jmood.20140907115343
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7624
dc.identifier.volume5en_US
dc.identifier.wosWOS:000421361100006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherYerkure Tanitim & Yayincilik Hizmetleri A Sen_US
dc.relation.ispartofJournal of Mood Disordersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectamotivational syndromeen_US
dc.subjectreward pathwayen_US
dc.subjectcannabis usageen_US
dc.titleAmotivational syndrome: less known and diagnosed as a clinicalen_US
dc.typeReview Articleen_US

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