The Investigation of Heat Shock Protein (HSP 27), Malondialdehyde (MDA), Nitric Oxide (NO) and Interleukin (IL-6, IL-10) Levels in Cattle with Anaplasmosis

dc.contributor.authorErgoenuel, Sema
dc.contributor.authorAskar, Tuenay Kontas
dc.date.accessioned2024-09-18T19:54:18Z
dc.date.available2024-09-18T19:54:18Z
dc.date.issued2009
dc.departmentHatay Mustafa Kemal Ãœniversitesien_US
dc.description.abstractBlood parasitic diseases such as tropical theileriosis in cattles are observed in Turkey. On the other hand. babesiosis and anaplasmaosis are other primer tick-borne diseases. Anaplasmosis is generalised in all over the region of Turkey. In the present study. we aimed to reveal the alterations of immune system and oxidative stress in cattles; with anaplasmosis by analysing heat shock protein (HSP 27), malondialdehyde (MDA), nitric oxide (NO), interleukin-6 (IL-6) and interleukin-10 (IL-10) levels The research has been performed on 15 healthy and 15 cattles with anaplasmosis, aged 1-3 year's old. The plasma levels of malondialdehyde and nitric oxide were determined by spectrophotometric methods while the concentrations of heat shock protein and interleukin (IL-6 and IL-10) were detected by using commercial ELISA kits. The levels of plasma MDA (P < 0.001), NO (P < 0.001). HSP 27 (P < 0.01) and serum IL-6 levels were determined significantly higher in cattles with anaplasmosis than the control group. The levels of serum IL-10 was not showed significant differences between the control and the patient group. The increases in the levels of malondialdehyde, nitric oxide, HSP 27 and interleukin-6 of the cattles with anaplasmosis may indicate the stimulation of host immune system and the existence of oxidative stress. In conclusion, determination of the levels of malondialdehyde, nitric oxide, HSP 27 and interleukin-6 might be a indicator for diagnosis of cattle anaplasmosis.en_US
dc.identifier.endpage579en_US
dc.identifier.issn1300-6045
dc.identifier.issue4en_US
dc.identifier.startpage575en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7643
dc.identifier.volume15en_US
dc.identifier.wosWOS:000271098600015en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherKafkas Univ, Veteriner Fakultesi Dergisien_US
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnaplasmosisen_US
dc.subjectCattleen_US
dc.subjectNitric oxideen_US
dc.subjectMalondialdehyde Heat shock proteinen_US
dc.subjectInterleukinen_US
dc.titleThe Investigation of Heat Shock Protein (HSP 27), Malondialdehyde (MDA), Nitric Oxide (NO) and Interleukin (IL-6, IL-10) Levels in Cattle with Anaplasmosisen_US
dc.typeArticleen_US

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