Effect of Local Gentamicin Application on Healing and Wound Infection in Patients with Modified Radical Mastectomy: a Prospective Randomized Study

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dc.authoridOzkan, Orhan Veli/0000-0002-2862-294X
dc.contributor.authorYetim, I.
dc.contributor.authorOzkan, O. V.
dc.contributor.authorDervisoglu, A.
dc.contributor.authorErzurumlu, K.
dc.contributor.authorCanbolant, E.
dc.date.accessioned2024-09-18T20:25:20Z
dc.date.available2024-09-18T20:25:20Z
dc.date.issued2010
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThis study investigated the effects of Gentacoll implants on healing in patients (n = 44) undergoing modified radical mastectomy and axillary dissection. Group I, the Gentacoll group (n = 22), underwent surgery followed by insertion of 10 x 10 x 0.5 cm Gentacoll implants (280 mg collagen sponge plus 200 mg gentamicin sulphate) into the axillary area and under the flap area of the breast before wound closure. Group II, the control group (n = 22), underwent surgery without the application of Gentacoll. Neither group received oral or parenteral post-operative antibiotic therapy. Outcome measures included wound infection, seroma formation, total drainage volumes, drain removal time and duration of hospital stay. Postoperative infection rate, seroma formation, drainage volumes and duration of hospital stay were significantly reduced in the Gentacoll group compared with the control group. In conclusion, the application of Gentacoll significantly improved postoperative outcomes in patients undergoing modified radical mastectomy.en_US
dc.identifier.doi10.1177/147323001003800426
dc.identifier.endpage1447en_US
dc.identifier.issn0300-0605
dc.identifier.issn1473-2300
dc.identifier.issue4en_US
dc.identifier.pmid20926017en_US
dc.identifier.scopus2-s2.0-77957783186en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1442en_US
dc.identifier.urihttps://doi.org/10.1177/147323001003800426
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10246
dc.identifier.volume38en_US
dc.identifier.wosWOS:000283025000026en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofJournal of International Medical Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGENTACOLLen_US
dc.subjectGENTAMICINen_US
dc.subjectANTIBIOTICSen_US
dc.subjectBREAST CANCERen_US
dc.subjectMODIFIED RADICAL MASTECTOMYen_US
dc.subjectCOLLAGEN SPONGESen_US
dc.subjectPOST-OPERATIVE INFECTIONen_US
dc.titleEffect of Local Gentamicin Application on Healing and Wound Infection in Patients with Modified Radical Mastectomy: a Prospective Randomized Studyen_US
dc.typeArticleen_US

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