Do alpha-1 antagonist medications affect the success of semi-rigid ureteroscopy? A prospective, randomised, single-blind, multicentric study

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dc.authoridAydin, Mustafa/0000-0002-4183-6045
dc.authoridYavuz, Abdulmecit/0000-0001-6141-3931
dc.authoridKilinc, Muhammet Fatih/0000-0002-2515-7106
dc.contributor.authorAydin, Mustafa
dc.contributor.authorKilinc, Muhammet Fatih
dc.contributor.authorYavuz, Abdulmecit
dc.contributor.authorBayar, Goksel
dc.date.accessioned2024-09-18T20:56:55Z
dc.date.available2024-09-18T20:56:55Z
dc.date.issued2018
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe objective of this study is to assess the efficacy of adjunctive silodosin therapy in improving the success rate of semi-rigid ureteroscopy for removing ureteral stones. Prospective randomised controlled clinical trial performed between July 2016 and September 2016. All the patients underwent ureteroscopic holmium lithotripsy with a YAG laser. The patients were randomised into one of three groups: those who did not use an alpha-1 blocker (AB) (Group 1, n = 50), those who used an AB for one day (Group 2, n = 50), and those who used an AB for three days (Group 3, n = 47). The following information was recorded for each patient: the side, location, and surface area of the stone; successful access; operative success; complications; and operative time. There were no significant differences between the three groups in terms of demographics, stone location or size, and number of doses of an analgesic drug used. Access to the stone and the stone-free rate were significantly higher in group 3 (95.7, 93.6%) than in group 1 (76, 74%) and group 2 (78, 74%) (p = 0.018, p = 0.021), respectively. Balloon dilatation and complication rates were significantly lower in group 3 (12.8, 0%) than in group 1 (34, 12%) and group 2 (22, 4%) (p = 0.045, p = 0.029), respectively. The use of silodosin for 3 days before ureteroscopy for ureteral stones increased the rate of access to all ureter stones and decreased the complication rate.en_US
dc.identifier.doi10.1007/s00240-017-1026-6
dc.identifier.endpage572en_US
dc.identifier.issn2194-7228
dc.identifier.issn2194-7236
dc.identifier.issue6en_US
dc.identifier.pmid29151116en_US
dc.identifier.startpage567en_US
dc.identifier.urihttps://doi.org/10.1007/s00240-017-1026-6
dc.identifier.urihttps://hdl.handle.net/20.500.12483/12178
dc.identifier.volume46en_US
dc.identifier.wosWOS:000447089600008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofUrolithiasisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSemi-rigid ureteroscopyen_US
dc.subjectUreter stoneen_US
dc.subjectAlpha-1 blockeren_US
dc.subjectSilodosinen_US
dc.titleDo alpha-1 antagonist medications affect the success of semi-rigid ureteroscopy? A prospective, randomised, single-blind, multicentric studyen_US
dc.typeArticleen_US

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