Scleredema Diabeticorum Partially Treated with Low-Dose Methotrexate: a Report of Five Cases

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dc.contributor.authorDogramaci, Asena Cigdem
dc.contributor.authorInan, Mehmet Ugur
dc.contributor.authorAtik, Esin
dc.contributor.authorGokce, Cumali
dc.date.accessioned2024-09-18T20:56:53Z
dc.date.available2024-09-18T20:56:53Z
dc.date.issued2012
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractScleredema is a rare connective tissue disorder that belongs to a group of scleroderma-like disorders. Although no known curative therapy exists, various specific treatments have been proposed in the literature. In this report, we describe five cases of scleredema partially treated with low-dose methotrexate therapy. All patients have diabetes mellitus type II. All patients were started on methotrexate 15 mg subcutaneously once weekly for 3 months. Biopsy specimens were taken from all patients and were examinated histologically before the treatment and after 3 months of treatment. All cases partially responded to low-dose methotrexate therapy. We believe that methotrexate therapy may be an alternative therapeutic options in scleredema in view of its efficacy.en_US
dc.identifier.doi10.5152/balkanmedj.2011.027
dc.identifier.endpage221en_US
dc.identifier.issn2146-3123
dc.identifier.issn2146-3131
dc.identifier.issue2en_US
dc.identifier.pmid25207001en_US
dc.identifier.scopus2-s2.0-84863094100en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage218en_US
dc.identifier.urihttps://doi.org/10.5152/balkanmedj.2011.027
dc.identifier.urihttps://hdl.handle.net/20.500.12483/12150
dc.identifier.volume29en_US
dc.identifier.wosWOS:000315504700024en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectScleredemaen_US
dc.subjectlow-dose methotrexateen_US
dc.subjectdiabetes mellitusen_US
dc.titleScleredema Diabeticorum Partially Treated with Low-Dose Methotrexate: a Report of Five Casesen_US
dc.typeEditorial Materialen_US

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