The relationship between coenzyme Q10 and severity of coronary artery disease

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dc.authorscopusid16041293500
dc.authorscopusid36503912900
dc.authorscopusid22937533800
dc.authorscopusid36611305900
dc.authorscopusid45861219100
dc.authorscopusid35361774100
dc.authorscopusid53864637500
dc.contributor.authorBüyükkaya, Eyüp
dc.contributor.authorEvliyao?lu, Osman
dc.contributor.authorIslamo?lu, Yahya
dc.contributor.authorCil, Habib
dc.contributor.authorKarakaş, Mehmet Fatih
dc.contributor.authorAkçay, Adnan Burak
dc.contributor.authorBilen, Perihan
dc.date.accessioned2024-09-19T15:43:34Z
dc.date.available2024-09-19T15:43:34Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractAim To evaluate the relationship between the levels of plasma coenzyme Q10 (CoQ10), a known antioxidant, and severity of the coronary atherosclerosis (AS) measured by Gensini score. Methods Patients with coronary artery disease (CAD) were enrolled to the study between 2010 and 2011 in cardiology outpatient clinics. They were admitted for diagnostic coronary angiography or angioplasty for typical indications. The Gensini scoring system was used to calculate CAD severity. Serum CoQ10, total cholesterol (TC), HDL cholesterol, LDL cholesterol, and triglyceride levels were assessed. Results One hundred thirteen subjects (83 CAD, 30 controls) were included. The patients with CAD were separated into three groups according to Gensini score. The serum levels of CoQ10, CoQ10/ TC, CoQ10/LDL-C, CoQ10/TG rates in the subjects of mild and severe AS groups were significantly lower than the control group (p<0.016 for all control vs. AS group comparisons). There were no significant differences in serum levels of CoQ10 and CoQ10/ TC, CoQ10/LDL-C, CoQ10/TG rates between the mild and severe AS groups. Conclusion This study revealed that although the serum CoQ10 levels were lower in stable CAD, there was no relationship between the severity of CAD and serum CoQ10 levels in patients with stable angina pectoris.en_US
dc.identifier.endpage233en_US
dc.identifier.issn1840-2445
dc.identifier.issue2en_US
dc.identifier.pmid23892836en_US
dc.identifier.scopus2-s2.0-84880751050en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage229en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14421
dc.identifier.volume10en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofMedicinski Glasniken_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidanten_US
dc.subjectAtherosclerosisen_US
dc.subjectGensini scoreen_US
dc.titleThe relationship between coenzyme Q10 and severity of coronary artery diseaseen_US
dc.typeArticleen_US

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