Selected biochemical and oxidative stress parameters and ceruloplasmin as acute phase protein associated with bovine leukaemia virus infection in dairy cows

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dc.contributor.authorAkalin, Pinar Peker
dc.contributor.authorAtaseven, Veysel Soydal
dc.contributor.authorDogan, Firat
dc.contributor.authorErgun, Yasar
dc.contributor.authorBaspinar, Nuri
dc.contributor.authorOzcan, Oguzhan
dc.date.accessioned2024-09-18T20:08:06Z
dc.date.available2024-09-18T20:08:06Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe aim of this study was to determine the ceruloplasmin (Cp) and vitamin C concentrations, the total antioxidant status (TAS), and selected biochemical parameters in dairy cows spontaneously infected with bovine leukaemia virus (BLV). Of the 27 cows included in the study, 18 animals were seropositive for enzootic bovine leukosis (EBL), whereas nine cows were seronegative and were used as controls. The serum aspartate aminotransferase (AST) (P = 0.003) and Cp concentrations (P = 0.03) decreased (65.17 +/- 5.03 and 7.70 +/- 0.72 respectively) in BLV-infected cows, as compared to healthy animals (100.67 +/- 11.50 and 10.40 +/- 0.70 respectively). A slight insignificant increase in alkaline phosphatase activity and unchanged levels of alanine aminotransferase, lactate dehydrogenase, calcium, magnesium, and TAS were demonstrated in EBL cows. As the TAS and vitamin C levels remained unchanged in EBL cows, it may be suggested that ruminants may compensate for the impaired oxidative/antioxidative balance. The results obtained also indicate that BLV may suppress AST and Cp synthesis or secretion in the liver through an unlcnown mechanism. The mechanism of action of BLV in hepatocytes, especially on AST and Cp, requires further investigation to elucidate the immune suppression caused by oncogenic retroviruses.en_US
dc.identifier.doi10.1515/bvip-2015-0048
dc.identifier.endpage330en_US
dc.identifier.issn0042-4870
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84943543012en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage327en_US
dc.identifier.urihttps://doi.org/10.1515/bvip-2015-0048
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8626
dc.identifier.volume59en_US
dc.identifier.wosWOS:000362155200001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherNatl Veterinary Research Insten_US
dc.relation.ispartofBulletin of The Veterinary Institute in Pulawyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectcattleen_US
dc.subjectbovine leukaemia virusen_US
dc.subjectaspartate aminotransferaseen_US
dc.subjectoxidative stressen_US
dc.subjectceruloplasminen_US
dc.titleSelected biochemical and oxidative stress parameters and ceruloplasmin as acute phase protein associated with bovine leukaemia virus infection in dairy cowsen_US
dc.typeArticleen_US

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