Relationship between elastic properties of the aorta and uric acid levels in newly diagnosed hypertensive patients

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dc.authoridDemirbag, Recep/0000-0001-7831-2715
dc.contributor.authorGur, Mustafa
dc.contributor.authorYilmaz, Remzi
dc.contributor.authorDemirbag, Recep
dc.contributor.authorSeyfeli, Ergun
dc.contributor.authorOzdogru, Ibrahim
dc.contributor.authorAltiparmak, Ibrahim Halil
dc.contributor.authorDogan, Ali
dc.date.accessioned2024-09-18T20:02:33Z
dc.date.available2024-09-18T20:02:33Z
dc.date.issued2006
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjectives: The association between elastic properties of the aorta and uric acid levels was investigated in patients with newly diagnosed hypertension. Study design: The study included 109 patients (68 females, 41 males; mean age 51.6+/-6.9 years) with newly diagnosed hypertension. Echocardiographic examination was performed. Systolic and diastolic diameters were measured by M-mode echocardiography, and elastic indices (aortic strain and distensibility) were calculated. Pulse pressure was obtained by a sphygmomanometer. Blood samples were obtained to determine serum uric acid levels and other biochemical parameters. The results were compared with those of a control group consisting of 21 age-and sex-matched healthy volunteers. Results: Compared to the control group, aortic strain and distensibility were significantly lower (p<0.001) and uric acid levels were significantly higher (p=0.044) in hypertensive patients. In multivariate regression analysis, aortic strain and distensibility showed independent relationships with uric acid levels (p=0.010 and p=0.009, respectively), age (p=0.001 and p<0.001), and left ventricular mass index (p=0.002 and p<0.001) in the patient group. Multivariate analysis according to gender showed that aortic strain and distensibility were in independent relationship with uric acid levels, age, and left ventricular mass index only in female patients. Conclusion: These data support the view that increased uric acid levels may have a role in the pathogenesis of impaired elastic properties of the aorta especially in hypertensive women.en_US
dc.identifier.endpage229en_US
dc.identifier.issn1016-5169
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-39749083317en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage223en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7853
dc.identifier.volume34en_US
dc.identifier.wosWOS:000421486200003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherTurkish Soc Cardiologyen_US
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivi-Archives of The Turkish Society of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAorta/physiopathologyen_US
dc.subjectelasticityen_US
dc.subjecthypertension/complicationsen_US
dc.subjecthyperuricemia/complicationsen_US
dc.subjecturic acid/blooden_US
dc.titleRelationship between elastic properties of the aorta and uric acid levels in newly diagnosed hypertensive patientsen_US
dc.typeArticleen_US

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