Oxidative Stress and Biochemical Alterations in Patients with Head and Multiple Organ Traumas

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dc.contributor.authorAkyuva, Yener
dc.contributor.authorNur, Gokhan
dc.contributor.authorDeveci, Haci Ahmet
dc.contributor.authorGuler, Songul Kocabas
dc.date.accessioned2024-09-18T20:04:26Z
dc.date.available2024-09-18T20:04:26Z
dc.date.issued2023
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractAIM: To evaluate paraoxonase (PON), total antioxidant status (TAS), total oxidant status (TOS), high-density lipoproteins (HDL), CRP, AST, ALT, GGT, ALP levels in patients with head and multiple organ traumas.MATERIAL and METHODS: The study included 29 male patients undergoing treatment for head and multiple organ traumas. Blood sample analysis was performed on the first, third, and seventh days after trauma.RESULTS: The mean age, duration of hospitalization in the intensive care unit, and intubation period of the study sample was 45 years (range: 9 to 81 years), 4.29 days, and 2.94 days, respectively. One patient died, and 13 underwent surgical intervention. Comparison of PON, TAS, TOS, and CRP levels showed statistically significant differences between the first day and the third and seventh days, although no such differences were seen in HDL levels. A moderately positive correlation was observed between CRP/ AST, CRP/ALT and CRP/GGT, while a moderately negative correlation was seen between CRP/ALP.CONCLUSION: The findings of this study suggest that some oxidative parameters may play a significant role in the prognosis and follow-up of intensive care patients. Moreover, biochemical markers can provide important information about patient response to trauma.en_US
dc.identifier.doi10.5137/1019-5149.JTN.42560-22.2
dc.identifier.endpage861en_US
dc.identifier.issn1019-5149
dc.identifier.issue5en_US
dc.identifier.pmid37309638en_US
dc.identifier.scopus2-s2.0-85171679623en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage855en_US
dc.identifier.urihttps://doi.org/10.5137/1019-5149.JTN.42560-22.2
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8169
dc.identifier.volume33en_US
dc.identifier.wosWOS:001110014100005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Neurosurgical Socen_US
dc.relation.ispartofTurkish Neurosurgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiochemical alterationen_US
dc.subjectHead traumaen_US
dc.subjectMultiple traumasen_US
dc.subjectTotal antioxidant/oxidant levelen_US
dc.titleOxidative Stress and Biochemical Alterations in Patients with Head and Multiple Organ Traumasen_US
dc.typeArticleen_US

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