Morning blood pressure surge is associated independently with orthostatic hypotension in hypertensive patients under treatment

Basit Öğe Kaydı
dc.authoridDonmez, Yurdaer/0000-0003-4745-7801
dc.contributor.authorCaf, Hakan
dc.contributor.authorDonmez, Yurdaer
dc.contributor.authorGuler, Emel Celiker
dc.contributor.authorKaypakli, Onur
dc.contributor.authorIcen, Yahya Kemal
dc.contributor.authorKoc, Mevluet
dc.date.accessioned2024-09-18T20:32:57Z
dc.date.available2024-09-18T20:32:57Z
dc.date.issued2018
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective Morning blood pressure surge (MBPS) and orthostatic hypotension (OH) play a role in the occurrence of cardiovascular events. We aimed to investigate the association between MBPS and OH in hypertensive patients under treatment. Patients and methods We prospectively included 297 patients (mean age: 53.8 +/- 10.7 years, male/female: 101/196) with essential hypertension. Tilt table testing was performed for the diagnosis of OH. OH was classified into three groups as initial OH (0-15s), classical OH (15s to 3 min), and delayed OH (3-30 min). Patients were categorized into two main groups: patient with OH or without OH. We used sleep-through MBPS. The MBPS was calculated as the difference between the average blood pressure (BP) during the 2 h after awakening and the lowest night-time BP. Results We detected initial OH in two patients, classic OH in seven patients, delayed OH in 20 patients, and delayed OH with syncope in two patients. MBPS, thiazide diuretic, and alpha-blocker treatments were found to be associated independently with the occurrence of OH. Every 10 mmHg increase in MBPS was found to increase the rate of development of OH by 29.6%. The cut-off value of MBPS obtained by the receiver operator characteristic curve analysis was 35mmHg for the prediction of OH occurrence (sensitivity: 58.0%, specificity: 68.0%). The area under the curve was 0.657 (95% confidence interval: 0.553-0.771, P=0.004). Conclusion OH is a major problem in hypertensive patients. Increased MBPS, which can be detected easily by 24-h ambulatory BP monitor, predicts the occurrence of OH independently. Copyright (C) 2018 Wolters Kluwer Health, Inc. All rights reserved.en_US
dc.identifier.doi10.1097/MBP.0000000000000326
dc.identifier.endpage197en_US
dc.identifier.issn1359-5237
dc.identifier.issn1473-5725
dc.identifier.issue4en_US
dc.identifier.pmid29738355en_US
dc.identifier.scopus2-s2.0-85050124311en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage191en_US
dc.identifier.urihttps://doi.org/10.1097/MBP.0000000000000326
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11227
dc.identifier.volume23en_US
dc.identifier.wosWOS:000438531400003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofBlood Pressure Monitoringen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectmorning blood pressure surgeen_US
dc.subjectorthostatic hypotensionen_US
dc.subjecthypertensionen_US
dc.titleMorning blood pressure surge is associated independently with orthostatic hypotension in hypertensive patients under treatmenten_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ N/A ]
İsim:
Tam Metin / Full Text
Boyut:
141.87 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu