Evaluation of inflammation during fixed orthodontic treatment

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dc.authoriday, yazgi/0000-0002-1455-9855
dc.authoridYilmaz, Hakki/0000-0002-4666-8247
dc.contributor.authorBilgic, Fundagul
dc.contributor.authorSozer, Ozlem Akinci
dc.contributor.authorOzcan, Oguzhan
dc.contributor.authorGurpinar, Ahmet Burak
dc.contributor.authorYilmaz, Hakki
dc.contributor.authorAy, Yazgi
dc.date.accessioned2024-09-18T20:26:50Z
dc.date.available2024-09-18T20:26:50Z
dc.date.issued2016
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to assess effects of fixed orthodontic therapy on high-sensitivity C-reactive protein (hs-CRP) level, CBC parameters and levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), gamma glutamyl transferase (GGT), alkaline phosphatase (ALP), urea, creatinine, sodium (Na), potassium (K), calcium (Ca), total protein (TP), and albumin (Alb). Design: Blood samples (7 ml) were drawn at baseline, on days 1 and 7, and three months after placement of braces in the study group, while only one blood sample was drawn at baseline in the control group. Serum hs-CRP levels were measured by nephelometric method. Friedman two-way variance analysis was used to assess values with skewed distribution obtained at baseline, on days 1 and 7, in the third month. Wilcoxon rank sign test was performed if median values were unequal. Results: During measurement periods, there were significant increases in hs-CRP level, WBC count and neutrophil count while a significant decrease in Na level (p < 0.05). K level was significantly decreased on the day 1. No significant differences were detected in other biochemical parameters evaluated. Conclusion: Elevation in serum hs-CRP levels and neutrophil: lymphocyte ratio within first 3 months indicates that a systemic immune response develops against therapy in patients undergoing fixed orthodontic therapy. (C) 2016 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.archoralbio.2016.07.004
dc.identifier.endpage58en_US
dc.identifier.issn0003-9969
dc.identifier.issn1879-1506
dc.identifier.pmid27447681en_US
dc.identifier.scopus2-s2.0-84978524627en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage54en_US
dc.identifier.urihttps://doi.org/10.1016/j.archoralbio.2016.07.004
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10560
dc.identifier.volume71en_US
dc.identifier.wosWOS:000385328200008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofArchives of Oral Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecths-CRPen_US
dc.subjectOrthodonticsen_US
dc.subjectBlood samplesen_US
dc.titleEvaluation of inflammation during fixed orthodontic treatmenten_US
dc.typeArticleen_US

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