Markers of Target Organ Damage in Children with Essential Hypertension

Basit Öğe Kaydı
dc.authoridcelakil, mehtap/0000-0002-5354-1455
dc.contributor.authorCelakil, Mehtap
dc.contributor.authorTaktak, Aysel
dc.date.accessioned2024-09-18T20:19:52Z
dc.date.available2024-09-18T20:19:52Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractIntroduction: Hypertension (HT) is a common health problem that may cause target-organ damages (TOD). Our study aimed to investigate the clinical, laboratory and radiological findings associated with TOD. Materials and Methods: The medical records of 102 patients diagnosed with essential HT were analyzed. Results: A total of 102 patient were evaluated in this study. There was 53 girls (%52) and 49 boys (%48); the mean age was 13.7 +/- 1.97 years. Twenty-five patients (24.5%) were dipper and 77 (75.5%) were non-dipper. Sixty-three patients (64%) had single TOD, 22 (21.6%) had two TOD and 9 (8.8%) had three TOD. For obesity, there was a significant difference between patients without TOD and those with TOD in all groups. Serum uric acid, creatinine and sodium levels were significantly higher in all groups with TOD than those without TOD. Similarly, the WBC/lymphocyte ratio was significantly higher among the. RI values were higher in all groups with TOD. Conclusion: The kidney is the first organ affected in essential HT and the earliest sign of TOD is microalbuminuria. Therefore, it may be possible to prevent other TOD that may occur if the kidney is well protected. In our study, the risk of developing TOD over time was found to be significantly higher in patients who did not have TOD at the time of diagnosis but had a high RI value. Reasonable adjustment of salt-protein balance and close monitoring of serum sodium, uric acid and creatine levels have prognostic importance in these patients.en_US
dc.identifier.doi10.4274/jcp.2022.34735
dc.identifier.endpage248en_US
dc.identifier.issn1304-9054
dc.identifier.issn1308-6308
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85146688110en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage242en_US
dc.identifier.urihttps://doi.org/10.4274/jcp.2022.34735
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9917
dc.identifier.volume20en_US
dc.identifier.wosWOS:000965719100002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofGuncel Pediatri-Journal of Current Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEssential hypertensionen_US
dc.subjecttarget organ damageen_US
dc.subjectprognosisen_US
dc.subjectchilden_US
dc.titleMarkers of Target Organ Damage in Children with Essential Hypertensionen_US
dc.typeReview Articleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Tam Metin / Full Text
Boyut:
336.08 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu