Correlation of Multiparametric Prostate MRI with Prostate Biopsy and Radical Prostatectomy Histopathology

Basit Öğe Kaydı
dc.contributor.authorSigva, Hakan
dc.contributor.authorGorur, Sadik
dc.contributor.authorGokalp, Fatih
dc.contributor.authorTamkac, Nezih
dc.contributor.authorPorgali, Sefa Burak
dc.contributor.authorYildirak, Ekrem
dc.date.accessioned2024-09-18T20:25:24Z
dc.date.available2024-09-18T20:25:24Z
dc.date.issued2024
dc.departmentHatay Mustafa Kemal Ãœniversitesien_US
dc.description.abstractObjective: Prostate cancer (PCa) is the most common cancer responsible for cancer deaths in men after lung cancer. In this study, we aimed to obtain information about the Gleason score of PCa by prostate image reporting and data system (PIRADS) scoring of multiparametric magnetic resonance imaging (mpMRI) by comparing mpMRI results with the histopathology of prostate biopsy and radical prostatectomy specimen. Materials and Methods: A total of 214 patients who applied to the outpatient clinic of Hatay Mustafa Kemal University Faculty of Medicine, Department of Urology between January 2019 and April 2021 with elevated prostate-specific antigen (PSA) levels were included in the study. All patients underwent mpMRI before the biopsy procedure. PIRADS scoring was performed by the same radiologist. Prostate biopsy was systematically performed by experienced urologists as 12 quadrant biopsies. Results: When the mpMRI results of the patients are evaluated; the most common patterns are seen as PIRADS 2 and PIRADS 4, followed by PIRADS 3 lesions, followed by PIRADS 5 lesions, and PIRADS 1 lesions, which were the least frequent. When the analysis was applied to predict PCa over the pyrans value, the receiver operating characteristics analysis result for the diagnosis of the disease showed statistically significant levels of area under the curve (0.860; p<0.001), with a sensitivity of 81% and a sensitivity of 3 and above PIRADS 3 and above. It can predict cancer with 75 specificity. In the correlation analysis, there was a low but significant correlation between PIRADS and PSA value (r=0.252; p<0.001). Conclusion: We found that patients presenting with elevated PSA levels and mpMRI had a high power in detecting PCa. We also found a strong relationship between ISUP rating and PIRADS. As a result, it is thought that the pathology of the patients can be predicted using mpMRI.en_US
dc.identifier.doi10.4274/uob.galenos.2024.2024.1.2
dc.identifier.endpage55en_US
dc.identifier.issn2147-2270
dc.identifier.issue2en_US
dc.identifier.startpage50en_US
dc.identifier.urihttps://doi.org/10.4274/uob.galenos.2024.2024.1.2
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10287
dc.identifier.volume23en_US
dc.identifier.wosWOS:001292819300002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofUroonkoloji Bulteni-Bulletin of Urooncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGleason scoreen_US
dc.subjectmultiparametric magnetic resonance imagingen_US
dc.subjectprostate canceren_US
dc.subjectradical prostatectomyen_US
dc.titleCorrelation of Multiparametric Prostate MRI with Prostate Biopsy and Radical Prostatectomy Histopathologyen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
Ä°sim:
Tam Metin / Full Text
Boyut:
165.31 KB
Biçim:
Adobe Portable Document Format
Ä°ndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu