Expression of Cell Proliferation Markers in Benign, Premalignant and Malignant Lesions and Human Papillomavirus Isolation

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dc.authoridDURMAZ, RIZA/0000-0001-6561-778X
dc.contributor.authorSerarslan, Gamze
dc.contributor.authorAtik, Esin
dc.contributor.authorOtlu, Baris
dc.contributor.authorBakaris, Sevgi
dc.contributor.authorDurmaz, Riza
dc.date.accessioned2024-09-18T20:26:52Z
dc.date.available2024-09-18T20:26:52Z
dc.date.issued2007
dc.departmentHatay Mustafa Kemal Ãœniversitesien_US
dc.description.abstractBackground and Design: This study was designed to investigate the role of proliferation markers in various benign, premalig- nant and malignant skin lesions and also aimed to detect HPV positivity in these lesions. Material and Method: A total of 62 paraffin blocks [12 seborrheic keratoses (SK), 10 keratoacantoma (KA), 8 actinic keratoses (AK), 22 basal cell carcinoma (BCC), and 10 squamous cell carcinoma (SCC)] were included in the study. Specimens were stud- ied immunohistochemically for the expression of Ki-67, p21 and bcl-2. PCR was performed to detect HPV DNA. Results: HPV positivity was detected in two tissues of BCC (HPV type-16). In the lesions, the Ki-67, p21 and bcl-2 expressions were found to be increased respectively: KAen_US
dc.identifier.endpage62en_US
dc.identifier.issn1019-214X
dc.identifier.issn1308-6294
dc.identifier.issue2en_US
dc.identifier.startpage57en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10570
dc.identifier.volume41en_US
dc.identifier.wosWOS:000217261600006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherDeri Zuhrevi Hastaliklar Dernegien_US
dc.relation.ispartofTurkderm-Turkish Archives of Dermatology and Venerologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHuman papilloma virusen_US
dc.subjectKi-67en_US
dc.subjectbcl-2en_US
dc.subjectp21en_US
dc.titleExpression of Cell Proliferation Markers in Benign, Premalignant and Malignant Lesions and Human Papillomavirus Isolationen_US
dc.typeArticleen_US

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