Metabolic deterioration just after infancy

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Küçük Resim

Tarih

2013

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Medi+World Int

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Background: We tried to understand whether or not there are some relationships between body weight alone and systolic and diastolic blood pressures (BP) and other metabolic parameters even in childhood. Methods: Consecutive children and adolescents between the ages of 2 and 15 years were studied. Patients with devastating illnesses were excluded to avoid their possible effects on weight. Cases were divided into the four groups according to their percentile for weight alone, including cases below the 3rd percentile in the first, below the 50th percentile in the second, at and above the 50th percentile in the third, and above the 97th percentile in the fourth group. Results: The study included 299 cases. Although mean values of the systolic and diastolic BPs, plasma glucose, total cholesterol, low density lipoprotein cholesterol, triglyceride, and alanine aminotransferase increased, mean value of the high density lipoprotein cholesterol decreased significantly from the first towards the fourth groups in a gradual manner nearly in all steps. Conclusion: Metabolic syndrome is a reversible progression step between complete physical health and irreversible terminal diseases with a very high prevalence in adults. But these findings suggest that pathophysiological mechanisms of the syndrome are already going on even in childhood, and bases of the syndrome are starting to be built up just after the period of infancy, probably due to the eating habits of the families. Therefore, because of the irreversible natures of the terminal diseases of the syndrome, the care to prevent should be started even in childhood.

Açıklama

Anahtar Kelimeler

Body weight, blood pressure, metabolic syndrome, infancy

Kaynak

World Family Medicine

WoS Q DeÄŸeri

N/A

Scopus Q DeÄŸeri

Cilt

11

Sayı

2

Künye