Overactive Bladder and Pontine Reticular Formation

Basit Öğe Kaydı
dc.contributor.authorZorba, Orhan Unal
dc.contributor.authorKirbas, Serkan
dc.contributor.authorUzun, Hakki
dc.contributor.authorCetinkaya, Mehmet
dc.contributor.authorOnem, Kadir
dc.contributor.authorRifaioglu, Mehmet Murat
dc.date.accessioned2024-09-18T20:53:02Z
dc.date.available2024-09-18T20:53:02Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground: The etiology of overactive bladder (OAB) remains unclear. Observed neurogenic factors in the literature are limited to suprapontine or spinal pathologies. The blink reflex is a useful tool in the evaluation of brainstem functions. Blink reflex latency times were evaluated in order to reveal pathology in the brainstem. Methods: A total of 60 women, 30 patients with idiopathic OAB and 30 healthy controls, were enrolled in the study. Blink reflex latency times were analyzed by electrical stimulation of the supraorbital nerve. Two responses in the orbicularis oculi muscle, early ipsilateral response (R1) and late bilateral response (R2) latency times, were recorded. Results: Mean ages of the patients and controls were 51.9 +/- 5.3 and 49.2 +/- 6.2 years, respectively. R2 latency times were significantly higher in patients than in controls. However, R1 latency times were similar between the two groups. Conclusions:The results of the study suggest a significant relation between late blink latencytimes and OAB. An oligosynaptic path via the trigeminal nuclei is responsible for R1; however, R2 response is relayed through the reticular formation. Stimulation of pontine reticular formation inhibits micturition contraction. In some patients, idiopathic OAB may result from reticular formation-originated pathology. Additional studies on other reticular formation-mediated reflexes are needed to reveal possible dysfunction of reticular formation. Copyright (C) 2013 S. Karger AG, Baselen_US
dc.identifier.doi10.1159/000350940
dc.identifier.endpage422en_US
dc.identifier.issn0042-1138
dc.identifier.issn1423-0399
dc.identifier.issue4en_US
dc.identifier.pmid24296362en_US
dc.identifier.scopus2-s2.0-84890068836en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage417en_US
dc.identifier.urihttps://doi.org/10.1159/000350940
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11546
dc.identifier.volume91en_US
dc.identifier.wosWOS:000327925400007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofUrologia Internationalisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOveractive bladderen_US
dc.subjectPonsen_US
dc.subjectReticular formationen_US
dc.subjectBlink reflexen_US
dc.titleOveractive Bladder and Pontine Reticular Formationen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ N/A ]
İsim:
Tam Metin / Full Text
Boyut:
115.28 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu