Elastographic evaluation of the effect of sickle cell anemia on testicles: a prospective study

Basit Öğe Kaydı
dc.authoridGokalp, Fatih/0000-0003-3099-3317
dc.authoridILGEZDI, Alican/0000-0002-2416-5534
dc.authoridTamkac, Nezih/0000-0001-6903-7010
dc.authoridILHAN, GUL/0000-0003-1616-6358
dc.authoridGORUR, Sadik/0000-0002-3458-5428
dc.authoridKacmaz, Murat/0000-0003-1111-8605
dc.authoridKoras, omer/0000-0001-9749-5254
dc.contributor.authorKoras, Omer
dc.contributor.authorGorur, Sadik
dc.contributor.authorBayramogullari, Hanifi
dc.contributor.authorIlhan, Gul
dc.contributor.authorGokalp, Fatih
dc.contributor.authorKacmaz, Murat
dc.contributor.authorIlgezdi, Alican
dc.date.accessioned2024-09-18T20:29:42Z
dc.date.available2024-09-18T20:29:42Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractTo quantitatively determine testicular tissue stiffness values using shear wave elastography (SWE) in males that have sickle cell anemia (SCA) and to evaluate the relationship between elastography results and semen analysis parameters and hormone levels. Fifty patients diagnosed with SCA and followed up in the hematology outpatient clinic were evaluated in the urology outpatient clinic as the study group. In addition, there were 88 patients without any SCA-related complaints in the control group. We compared these groups with respect to their values, spermiogram parameters, testicular volume, and SWE values. Among patients in the SCA group, 28% had impaired sperm parameters. When testicular elastography was assessed, the testicular volumes were materially lower in the SCA group in comparison to the control group [right testicular volume: 14.76 (12.77-18.12) and 19.68 (15.12-24.18), respectively, p < 0.001; left testicular volume: 14.11 (11.06-17.32) and 16.59 (13.38-20.13), respectively, p = 0.015]. Additionally, the left testis central stiffness and the left testis inferior stiffness were significantly higher in the SCA group (p < 0.001 and p = 0.014, respectively). The age and hydroxyurea use had a worse effect on sperm parameters in patients with SCA (odds ratio: -0.161 and -1.914, standard deviation: 0.071 and 0.921, and p = 0.024 and p = 0.038, respectively). We consider that the technique utilized in this study for SWE values is fast and can be adopted as a reliable diagnostic tool and follow-up practice in routine clinical practice to evaluate the acuteness of damage to the testicles in patients having SCA.en_US
dc.identifier.doi10.1111/and.14481
dc.identifier.issn0303-4569
dc.identifier.issn1439-0272
dc.identifier.issue8en_US
dc.identifier.pmid35610190en_US
dc.identifier.scopus2-s2.0-85130483693en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1111/and.14481
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11017
dc.identifier.volume54en_US
dc.identifier.wosWOS:000799659800001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAndrologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectmale infertilityen_US
dc.subjectshear wave elastographyen_US
dc.subjectsickle cell anemiaen_US
dc.subjecttestisen_US
dc.subjectultrasonographyen_US
dc.titleElastographic evaluation of the effect of sickle cell anemia on testicles: a prospective studyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu