Licorice induced hypokalemia, edema, and thrombocytopenia

dc.authoridkarakus, ali/0000-0003-1358-3201
dc.contributor.authorCelik, M. M.
dc.contributor.authorKarakus, A.
dc.contributor.authorZeren, C.
dc.contributor.authorDemir, M.
dc.contributor.authorBayarogullari, H.
dc.contributor.authorDuru, M.
dc.contributor.authorAl, M.
dc.date.accessioned2024-09-18T20:27:56Z
dc.date.available2024-09-18T20:27:56Z
dc.date.issued2012
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractLicorice originates from the root of Glycyrrhiza glabra, which has a herbal ingredient, glycyrrhizic acid, and has a mineralocorticoid-like effect. Chronic intake of licorice induces a syndrome similar to that found in primary hyperaldosteronism. Excessive intake of licorice may cause a hypermineralocorticoidismlike syndrome characterized by sodium and water retention, hypertension, hypokalemia, metabolic alkalosis, low-renin activity, and hypoaldosteronism. In this case report, an association of hypokalemia, edema, and thrombocytopenia that is developed due to the excessive intake of licorice is presented. There are case reports in the literature, which suggest that toxicity findings may emerge with hyperaldosteronism-like manifestations such as hypokalemia, edema, and hypertension. However, any knowledge of thrombocytopenia as a resultant was not encountered among these reported toxic effects. Our case is important because it shows that the excessive intake of licorice may cause a toxic effect in the form of thrombocytopenia. This report is the first presented case to show thrombocytopenia due to licorice syrup consumption.en_US
dc.identifier.doi10.1177/0960327112446843
dc.identifier.endpage1298en_US
dc.identifier.issn0960-3271
dc.identifier.issn1477-0903
dc.identifier.issue12en_US
dc.identifier.pmid22653692en_US
dc.identifier.scopus2-s2.0-84871570917en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1295en_US
dc.identifier.urihttps://doi.org/10.1177/0960327112446843
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10619
dc.identifier.volume31en_US
dc.identifier.wosWOS:000311762100013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofHuman & Experimental Toxicologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjecthypokalemiaen_US
dc.subjectlicoriceen_US
dc.subjectthrombocytopeniaen_US
dc.titleLicorice induced hypokalemia, edema, and thrombocytopeniaen_US
dc.typeArticleen_US

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