Effectivity of local bupivacaine infusion in the prevention of postoperative ileus

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dc.contributor.authorKilic, Erol
dc.contributor.authorKoca, Bulent
dc.date.accessioned2024-09-18T20:54:25Z
dc.date.available2024-09-18T20:54:25Z
dc.date.issued2019
dc.departmentHatay Mustafa Kemal Ãœniversitesien_US
dc.description.abstractAim: Inflammation is the predominant factor in the development of gastrointestinal dysmotility or postoperative ileus although dissection and neurological and inflammatory factors secondary to intestinal manipulation have been blamed. In this study, we investigated the effectivity of local bupivacaine infusion for prevention of postoperative ileus. Material and Method: This retrospective study included patients that underwent median laparotomy and received conventional analgesia alone or conventional analgesia followed by local bupivacaine. Patients that received conventional analgesia (nonsteroidal anti-inflammatory drugs (NSAIDs] + opioids) followed by local bupivacaine infusion (15 mg/h during 48h) with Pain buster pump system were classified as Group 1 (n=30) and the patients that received conventional analgesia alone ([NSAIDs) + opioids) were classified as Group 2 (n=31). Results: The groups were similar in terms of age, gender, preoperative ASA score, surgical technique, and operative time. The Visual Analog Scale (VAS) scores during the periods 8-24 and 24-48 h and the analgesic requirement during the periods 0-8, 8-24, and 24-48 h were significantly decreased in Group 1 compared to Group 2 (p<0.05). In Group 1, active postoperative bowel sounds started earlier (38 vs. 47 h) and mean time to first flatus/defecation was significantly lower than in Group 2 (64.13 +/- 9.06 vs. 77.90 +/- 10.25 h) (p<0.05). Discussion: Transfascial bupivacaine infusion appears to be an effective technique since it reduced early postoperative pain and postoperative analgesic requirement and also provided favorable effects in the prevention of postoperative ileus, thereby leading to shorter intensive care unit stay.en_US
dc.identifier.doi10.4328/JCAM.5980
dc.identifier.endpage112en_US
dc.identifier.issn1309-0720
dc.identifier.issn1309-2014
dc.identifier.issue1en_US
dc.identifier.startpage109en_US
dc.identifier.urihttps://doi.org/10.4328/JCAM.5980
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11795
dc.identifier.volume10en_US
dc.identifier.wosWOS:000451875800023en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherDerman Medical Publen_US
dc.relation.ispartofJournal of Clinical and Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPostoperative Ileusen_US
dc.subjectPostoperative Analgesiaen_US
dc.subjectTransfascial Bupivacaine Infusionen_US
dc.titleEffectivity of local bupivacaine infusion in the prevention of postoperative ileusen_US
dc.typeArticleen_US

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