Colistin administration for extensive drug-resistant Pseudomonas aeruginosa pneumonia in intensive care unit: case report

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dc.authoridUlutas, Kemal Turker/0000-0003-2852-0449
dc.contributor.authorKilinc, Cetin
dc.contributor.authorUlutas, Kemal Turker
dc.contributor.authorAkcimen, Beril
dc.contributor.authorCelik, Levent
dc.contributor.authorDuran, Nizami
dc.date.accessioned2024-09-18T20:55:31Z
dc.date.available2024-09-18T20:55:31Z
dc.date.issued2016
dc.departmentHatay Mustafa Kemal Ãœniversitesien_US
dc.description.abstractPseudomonas aeruginosa strains may develop the resistance to antibiotics via different mechanisms such as, alteration of protein binders of penicillin, porin mutations, DNA-gyrase mutation and active expulsion pumps. Especially, multi-drug resistant P. aeruginosa strains, are known to be most important cause of mortality in the intensive care units. Special antibiotic therapy is required, because of having the multiple antibiotic resistances. The case reports a 67-year-old male patient who had a history of 6 years paraplegia. He admitted to the emergency department with impaired general condition, including a week ongoing nausea, chest pain, cough, phlegm, wheezing and fatigue. Widespread crepitant rales were detected up to the middle and lower zones of both lungs. Besides, there was CRP elevation, hyperuricemia, a consolidated infiltration compatible with increased opacity at lower zone of right lung and reticulonodular style increased opacity at upper zone of right lung on chest. On disk diffusion, there was resistance to all antibiotics except colistin. Although colistin treatment was initiated, the patient was lost due to cardiac arrest at the 3rd day of treatment. This case is reported to be observed for the first time of P. aeruginosa infection that was extensively drug-resistant to antibiotics except colistin in our hospital, and to highlight importance of true treatment arrangements according to antibiotic susceptibility.en_US
dc.identifier.endpage182en_US
dc.identifier.issn2602-3032
dc.identifier.issn2602-3040
dc.identifier.issue1en_US
dc.identifier.startpage178en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11892
dc.identifier.volume41en_US
dc.identifier.wosWOS:000373128700031en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherCukurova Univ, Fac Medicineen_US
dc.relation.ispartofCukurova Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPseudomonas aeruginosaen_US
dc.subjectintensive careen_US
dc.subjectdrug resistanceen_US
dc.subjectcolistinen_US
dc.titleColistin administration for extensive drug-resistant Pseudomonas aeruginosa pneumonia in intensive care unit: case reporten_US
dc.typeArticleen_US

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