Formulation and Characterization of Niacinamide and Collagen Emulsion and Its Investigation as a Potential Cosmeceutical Product

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dc.authoridPOPA, LACRAMIOARA/0000-0002-3139-9865
dc.authoridGHICA, Mihaela Violeta/0000-0001-6853-9203
dc.authoridAlbu, Madalina Georgiana/0000-0001-9960-2244
dc.authoridComan, Alina Elena/0000-0003-1062-3650
dc.authoridAnuta, Valentina/0000-0003-1266-5862
dc.contributor.authorDanila, Elena
dc.contributor.authorKaya, Durmus Alpaslan
dc.contributor.authorAnuta, Valentina
dc.contributor.authorPopa, Lacramioara
dc.contributor.authorComan, Alina Elena
dc.contributor.authorChelaru, Ciprian
dc.contributor.authorConstantinescu, Rodica Roxana
dc.date.accessioned2024-09-18T20:13:24Z
dc.date.available2024-09-18T20:13:24Z
dc.date.issued2024
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractCosmeceuticals are one of the fast-growing areas of the natural personal care industry. Cosmeceuticals are cosmetic products with medicinal or drug-like benefits that can affect the biological functioning of the skin depending on the ingredients in the composition. The development of one formulation acting on the dermis and stimulating the collagen production is very important for the hydration of the skin. The association of collagen with other ingredients can have a positive effect on increasing the natural production of collagen in the skin. An example of such an ingredient is niacinamide, which, having a recognized nutritional value, has been quite recently studied. Considering these aspects, this study focused on developing oil-in-water (O/W) emulsions, based on natural ingredients (vegetable oils, floral waters, and essential oils) and hydrolyzed collagen and niacinamide as active ingredients, and on evaluating the stability, pH, optical, superficial, rheological and textural properties, as well as microbiological tests of the emulsions, in order to investigate their potential as a cosmeceutical product. All the obtained emulsions proved to be stable at variable temperatures and had a pH value compatible with natural pH of the skin, allowing their safe application. Over goniometric analysis, a partial wetting and a hydrophilic character of the emulsions were emphasized. Following the rheological analyses, all dermatocosmetic emulsions exhibited non-Newtonian pseudoplastic behavior and a thixotropic character, these properties being very important for their production process and their application on the skin surface to generate an optimal therapeutic effect. The textural characteristics recorded for all emulsions indicated adequate spreadability at the application site. All tested samples respected the Pharmacopoeia limits of microbiological contamination. All prepared emulsions have good stability, are safe for the skin and have appropriate physicochemical and microbiological characteristics; therefore, they can be used as a cosmeceutical product.en_US
dc.description.sponsorshipMinistry of Research, Innovation and Digitalizationen_US
dc.description.sponsorshipNo Statement Availableen_US
dc.identifier.doi10.3390/cosmetics11020040
dc.identifier.issn2079-9284
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85192187618en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.3390/cosmetics11020040
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9155
dc.identifier.volume11en_US
dc.identifier.wosWOS:001210151700001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofCosmeticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectcosmeceuticalen_US
dc.subjectemulsionen_US
dc.subjectcollagen hydrolysateen_US
dc.subjectplant extractsen_US
dc.titleFormulation and Characterization of Niacinamide and Collagen Emulsion and Its Investigation as a Potential Cosmeceutical Producten_US
dc.typeArticleen_US

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