A New Molecule in Aneurysmal Subarachnoid Hemorrhage: Dendroaspis Natriuretic Peptide

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dc.authoridISIK, NEJAT/0000-0002-6809-4969
dc.authoridElmaci, Ilhan/0000-0001-9433-0307
dc.contributor.authorSerefhan, Alpay
dc.contributor.authorAltas, Murat
dc.contributor.authorCerci, Ajlan
dc.contributor.authorIsik, Nejat
dc.contributor.authorElmaci, Ilhan
dc.date.accessioned2024-09-18T20:15:04Z
dc.date.available2024-09-18T20:15:04Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractAIM: Dendroaspis natriuretic peptide (DNP) is the most recently identified member of the natriuretic peptide family. Although DNP has similar structure and function to other members, it is genetically different. The other members are known to cause vasorelaxation but the effects of DNP on vascular structure still remains unclear. In this study, we aimed to find out the role of DNP in the development of vasospasm following aneurysmal SAH (subarachnoid hemorrhage). MATERIAL and METHODS: DNP levels of 17 patients diagnosed with aneurysmal SAH and 25 volunteers as control were measured. All SAH patients were treated with aneurysm clip. Five ml of venous blood sample was obtained on postoperative 1,3 and 7th days from each patient. Additionally, DNP levels were determined by obtaining cerebrospinal fluid (CSF) postoperative 1,3 and 7th days. RESULTS: Statistically significant difference was observed between cerebrospinal fluid DNP levels on day 1 and day 3 (P<0.05). CONCLUSION:This study suggests that DNP can be anticipated among molecules leading development of vasospasm. The findings of present study are believed to encourage further studies regarding receptors and receptor specific drugs.en_US
dc.identifier.doi10.5137/1019-5149.JTN.8016-13.2
dc.identifier.endpage43en_US
dc.identifier.issn1019-5149
dc.identifier.issue1en_US
dc.identifier.pmid24535789en_US
dc.identifier.scopus2-s2.0-84894046385en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage38en_US
dc.identifier.urihttps://doi.org/10.5137/1019-5149.JTN.8016-13.2
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9428
dc.identifier.volume24en_US
dc.identifier.wosWOS:000331663300009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Neurosurgical Socen_US
dc.relation.ispartofTurkish Neurosurgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDendroaspis natriuretic peptideen_US
dc.subjectVasospasmen_US
dc.subjectAneurysmal subaracnoid hemorrhageen_US
dc.titleA New Molecule in Aneurysmal Subarachnoid Hemorrhage: Dendroaspis Natriuretic Peptideen_US
dc.typeArticleen_US

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