Does the neutrophil-to-lymphocyte ratio have any importance between subjects with obstructive sleep apnea syndrome with obesity and without obesity?

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dc.contributor.authorBozkus, Fulsen
dc.contributor.authorDikmen, Nursel
dc.contributor.authorSamur, Anil
dc.contributor.authorBilal, Nagihan
dc.contributor.authorAtilla, Nurhan
dc.contributor.authorArpag, Hseyin
dc.date.accessioned2024-09-18T20:52:49Z
dc.date.available2024-09-18T20:52:49Z
dc.date.issued2018
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractIntroduction: An increase in the incidence of OSAS (obstructive sleep apnoea syndrome) has been seen due to the reported association between OSAS and obesity. Subjects are predisposed to cardiovascular disease due to systemic inflammation caused by the interactions between obesity and OSA. Inflammatory markers could be used to predict the degree of systemic inflammation, which could be a prognostic factor for future adverse events such as metabolic risks. One marker that has recently started being used as an indicator of systemic inflammation is neutrophil-to-lymphocyte ratio (NLR). Materials and Methods: The aim is to evaluate NLR, which is a easily measured parameter of systemic inflammation in OSAS subjects with and without obesity. 155 subjects were assigned to four different groups according to their body mass indices. Comparisons of white blood cell, neutrophil, lymphocyte, NLR values and anthropometric measurements were done for each group. Results: The NLR and neutrophil counts of group 4 were statistically significant and higher than those of groups 1, 2 and 3. The lymphocyte counts of group 4 were the lowest amongst all groups, these values were lower than the lymphocyte counts of groups 1, 2 and 3 with statistically significant differences (p< 001). A positive correlation was found between the body mass index and lymphocyte count values of obese OSAS subjects (r= 0.027, p= 353). Conclusion: The NLR ratio was found to be increasing by obesity grade and reveals that the associated inflammatory response also increases. The NLR ratio might be used as an inflammatory marker in obese OSAS subjects.en_US
dc.identifier.doi10.5578/tt.66535
dc.identifier.endpage15en_US
dc.identifier.issn0494-1373
dc.identifier.issue1en_US
dc.identifier.pmid30020036en_US
dc.identifier.scopus2-s2.0-85049190534en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage8en_US
dc.identifier.urihttps://doi.org/10.5578/tt.66535
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11424
dc.identifier.volume66en_US
dc.identifier.wosWOS:000435396300002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Assoc Tuberculosis & Thoraxen_US
dc.relation.ispartofTuberkuloz Ve Torak-Tuberculosis and Thoraxen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectObesityen_US
dc.subjectOSAen_US
dc.subjectNeutrophil-to-lymphocyte ratioen_US
dc.titleDoes the neutrophil-to-lymphocyte ratio have any importance between subjects with obstructive sleep apnea syndrome with obesity and without obesity?en_US
dc.typeArticleen_US

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