Effects of the Bovine Amniotic Membrane on Corneal Healing with Acute Alkali Burns in Rabbits
[ N/A ]
Tarih
2009
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Medwell Online
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The Bovine Amniotic Membrane (BAM) was transplanted on the right comea of 8 adult rabbits after an alkali burn was created with 2.5 N NaOH. Density and area of the corneal opacity, area of the corneal epithelial defect, vascularization and complications were clinically evaluated. Left corneas of the same animals were used as active control group. At the end of the experiment, all the eyes were extirpated and histologically examined on light microscopy. BAM has decreased density and area of the corneal opacity and increased reepithelialisation, but promoted episcleral vasodilatation more prominently in clinical examination. Histologically; the distrubition of Polymorphonuclear (PMN) leucocytes, corneal thicknesses, edema, keratinization, neovascularization and inflammation were significantly reduced by BAM compared to active control group. BAM was highly found to be effective to restore the corneal surface with acute alkali burns in the rabbit.
Açıklama
Anahtar Kelimeler
Bovine Amniotic Membrane, BAM, transplantation, cornea, alkali burn, rabbit
Kaynak
Journal of Animal and Veterinary Advances
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
8
Sayı
8
