Evaluation of the relationship between thromboembolic risk score (CHA2DS2-VASc) and inflammation and coagulation markers in patients with non-valvular atrial fibrillation in emergency department

dc.authorscopusid56079924200
dc.authorscopusid57224249103
dc.authorscopusid56263212300
dc.authorscopusid57210550562
dc.authorscopusid55195666700
dc.authorscopusid42462275000
dc.authorscopusid55195666400
dc.contributor.authorYaman, Fatih Nazmi
dc.contributor.authorCivelek, Birol
dc.contributor.authorYavuz, Bunyamin
dc.contributor.authorYilmaz, Mustafa
dc.contributor.authorAtescelik, Metin
dc.contributor.authorSahan, Mustafa
dc.contributor.authorGoktekin, Mehmet Cagri
dc.date.accessioned2024-09-19T15:43:40Z
dc.date.available2024-09-19T15:43:40Z
dc.date.issued2016
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: To evaluate the relationship between CHA2DS2-VASc score and inflammation and coagulation markers in patients admitted to Emergency Department (ED) with non-valvular Atrial Fibrillation (AF). Methods and Results: Eighty-four patients with non-valvular AF were included in the study. CHA2DS2- VASc scores were calculated for these patients. In addition, plasma levels of BNP, hs-CRP, CRP, vWF and D-dimer were measured. The relationship between CHA2DS2-VASc score and these parameters were evaluated. Eleven (13%) patients were considered to be at low-risk due to CHA2DS2-VASc score being<2 and 73 (87%) patients were considered to be at high risk due to CHA2DS2-VASc score being ? 2. The mean age of patients was 68 ± 13 years and 50 (60%) of patients were male. Plasma BNP, hs-CRP, CRP, vWF and D-dimer levels were significantly higher in high-risk group. In addition, a significant positive correlation was found between CHA2DS2-VASc score and BNP (r=0.436, p<0.001), D-Dimer (r=0.356, p=0.003), hs-CRP (r=0.335, p=0.002), CRP (r=0,331, p=0.002), vWF (r=0.330, p=0.002) and patient age (r=0.573, p<0.001). Conclusion: It was found that BNP, hs-CRP, CRP, vWF and D-dimer levels increase significantly and that there is a positive correlation between CHA2DS2-VASc and these markers in high-risk patients with CHA2DS2-VASc score ? 2. © 2016, Scientific Publishers of India. All rights reserved.en_US
dc.identifier.endpage590en_US
dc.identifier.issn0970-938X
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84979060384en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage586en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14498
dc.identifier.volume27en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherScientific Publishers of Indiaen_US
dc.relation.ispartofBiomedical Research (India)en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAtrial fibrillationen_US
dc.subjectBNPen_US
dc.subjectCHA<sub>2</sub>DS<sub>2</sub>-VASc scoreen_US
dc.subjectD-Dimeren_US
dc.subjecths-CRPen_US
dc.subjectvWFen_US
dc.titleEvaluation of the relationship between thromboembolic risk score (CHA2DS2-VASc) and inflammation and coagulation markers in patients with non-valvular atrial fibrillation in emergency departmenten_US
dc.typeArticleen_US

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