Intravenous ketamine and local bupivacaine infiltration are effective as part of a multimodal regime for reducing post-tonsillectomy pain
dc.contributor.author | Inanoglu, Kerem | |
dc.contributor.author | Akkurt, B. Cagla Ozbakis | |
dc.contributor.author | Turhanoglu, Selim | |
dc.contributor.author | Okuyucu, Semsettin | |
dc.contributor.author | Akoglu, Ertap | |
dc.date.accessioned | 2024-09-18T20:08:18Z | |
dc.date.available | 2024-09-18T20:08:18Z | |
dc.date.issued | 2009 | |
dc.department | Hatay Mustafa Kemal Üniversitesi | en_US |
dc.description.abstract | Background: The aim of this study was to investigate the effects of a multimodal analgesic regimen, including intravenous ketamine and peritonsillar infiltration of bupivacaine, on post-tonsillectomy pain in children. Material/Methods: Ninety children aged 2-12 years, undergoing tonsillectomy, were enrolled in this randomized, controlled and double-blinded study. Group I (n=30) received intravenous and peritonsillar saline, group II (n=30) received intravenous saline and peritonsillar bupivacaine, and group III (n=30) received intravenous 0.5 mg/kg ketamine and peritonsillar 0.25% bupivacaine (3-5 ml per tonsil). Pain was evaluated using a modified Children's Hospital of Eastern Ontario Pain Scale (mCHEOPS) recorded 15 min and 1, 4, 12, 16, and 24 h postoperatively. Results: No difference was found in the demographic data among the groups. Group I patients who received intravenous and peritonsillar saline solution as placebo had higher pain scores at 15(th) min, and Ist and 4(th) h than group II, and at all time intervals, than group III (P<0.05). Patients in group III also had significantly lower pain scores than group II at all time intervals except at 15(th) min (P<0.05). Analgesic requirements and the time to first analgesia were also significantly (P<0.05) better in the ketamine group. Conclusions: Intravenous ketamine and peritonsillar infiltration with bupivacaine are safe and effective as part of a multimodal regime in reducing post-tonsillectomy pain. | en_US |
dc.identifier.endpage | CR543 | en_US |
dc.identifier.issn | 1643-3750 | |
dc.identifier.issue | 10 | en_US |
dc.identifier.pmid | 19789514 | en_US |
dc.identifier.scopus | 2-s2.0-70349972805 | en_US |
dc.identifier.scopusquality | Q1 | en_US |
dc.identifier.startpage | CR539 | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.12483/8763 | |
dc.identifier.volume | 15 | en_US |
dc.identifier.wos | WOS:000272605000012 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | Int Scientific Information, Inc | en_US |
dc.relation.ispartof | Medical Science Monitor | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | children | en_US |
dc.subject | tonsillectomy | en_US |
dc.subject | pain | en_US |
dc.subject | ketamine | en_US |
dc.subject | bupivacaine | en_US |
dc.title | Intravenous ketamine and local bupivacaine infiltration are effective as part of a multimodal regime for reducing post-tonsillectomy pain | en_US |
dc.type | Article | en_US |
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