Elevated Monocyte to High-density Lipoprotein Ratios as an Inflammation Markers for Schizophrenia Patients

dc.authoridKARAMAN, MEHMET AKIF/0000-0001-7405-5133
dc.contributor.authorSahpolat, Musa
dc.contributor.authorAyar, Duygu
dc.contributor.authorAri, Mustafa
dc.contributor.authorKaraman, Mehmet Akif
dc.date.accessioned2024-09-18T20:26:43Z
dc.date.available2024-09-18T20:26:43Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: Monocyte to high density lipoprotein ratio (MHR) is a new instrument for giving notice inflammation, which plays a main role in schizophrenia. Thus, in this study, our goal was to investigate the possible association between MHR and schizophrenia. Methods: The participants of this study consisted of 75 schizophrenia patients and 74 healthy individuals (control group). The Positive and Negative Syndrome Scale was used to collect data from the patient group. Complete blood count parameters and lipid profile were analyzed in all study participants. Results: The patients with schizophrenia had higher MHR values (15.04 +/- 3.31 in schizophrenia patients and 12.62 +/- 2.99 in controls; p = 0.001). Monocyte counts and MHR of the schizophrenia patients were significantly higher than the control group. There was a significant and positive correlation between age, body mass index, severity of disease and MHR. Conclusion: To our knowledge, this study was the first to demonstrate inflammatory markers such as MHR levels in schizophrenia patients. Both monocyte counts and MHR values in schizophrenia patients were higher than the control group. MHR might be an available and useful inflammatory marker to evaluate inflammation in schizophrenia patients.en_US
dc.identifier.doi10.9758/cpn.2021.19.1.112
dc.identifier.endpage116en_US
dc.identifier.issn1738-1088
dc.identifier.issn2093-4327
dc.identifier.issue1en_US
dc.identifier.pmid33508794en_US
dc.identifier.scopus2-s2.0-85101401198en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage112en_US
dc.identifier.urihttps://doi.org/10.9758/cpn.2021.19.1.112
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10500
dc.identifier.volume19en_US
dc.identifier.wosWOS:000614138000011en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKorean Coll Neuropsychopharmacologyen_US
dc.relation.ispartofClinical Psychopharmacology and Neuroscienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHigh density lipoproteinen_US
dc.subjectInflammationen_US
dc.subjectMonocyteen_US
dc.subjectSchizophreniaen_US
dc.titleElevated Monocyte to High-density Lipoprotein Ratios as an Inflammation Markers for Schizophrenia Patientsen_US
dc.typeArticleen_US

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