Alterations in serum levels of trace elements in Cutaneous leishmaniasis patients in endemic region of Hatay (Antioch)

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dc.authoridYALIN, Ali Erdinc/0000-0002-3351-6885
dc.contributor.authorCulha, Gulnaz
dc.contributor.authorYalin, Erdinc
dc.contributor.authorSanguen, Kemal
dc.date.accessioned2024-09-18T20:13:41Z
dc.date.available2024-09-18T20:13:41Z
dc.date.issued2008
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractImmune cells, like all other types of cells, require an adequate supply of trace elements for the structure and function of metalloproteins that participate in housekeeping processes such as energy production and protection against reactive oxygen species. In addition, trace elements are required for the activity of a number of enzymes that directly participate in host defense processes. In the present study we evaluated the alterations of zinc, copper, selenium and iron concentrations in serum of patients treated with meglumine antimonate (glucantime) and untreated cutaneous leishmaniasis. Serum levels of zinc, copper, selenium and iron were measured by atomic emission spectrometer. The serum levels of these elements were found to be significantly higher in untreated patients compared to those of healthy controls. However, the levels of zinc, copper and iron in serum were significantly reuced and selenium levels were increased in treated patients. These suggest that the increasing levels of trace elements in serum may be host defense strategies of organism infection. In addition the high trace element levels were a sequel of the disease rather than a cause.en_US
dc.identifier.endpage3108en_US
dc.identifier.issn0970-7077
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-54049157965en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage3104en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9323
dc.identifier.volume20en_US
dc.identifier.wosWOS:000259602400084en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAsian Journal Of Chemistryen_US
dc.relation.ispartofAsian Journal of Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCutaneous leishmaniasisen_US
dc.subjecttrace elementsen_US
dc.subjectHatay (Antioch)en_US
dc.titleAlterations in serum levels of trace elements in Cutaneous leishmaniasis patients in endemic region of Hatay (Antioch)en_US
dc.typeArticleen_US

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