Effects of thymol and carvacrol on sperm quality and oxidant/antioxidant balance in rats

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dc.authoridGOKCEK, ISHAK/0000-0002-0590-6405
dc.authoridGUVENC, MEHMET/0000-0002-9716-0697
dc.contributor.authorGuvenc, Mehmet
dc.contributor.authorCellat, Mustafa
dc.contributor.authorGokcek, Ishak
dc.contributor.authorYavas, Ilker
dc.contributor.authorOzsoy, Yule Yurdagul
dc.date.accessioned2024-09-18T20:59:26Z
dc.date.available2024-09-18T20:59:26Z
dc.date.issued2019
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractIn this study, we have investigated the effects of different doses of thymol (T) and carvacrol (C) on sperm quality oxidative stress and antioxidant system. For this purpose, 49 rats were divided into seven groups (7 rats in each group): 1st Group (control); 2nd Group T-10 (thymol 10?mg/kg), 3rd Group T-20 (thymol 20?mg/kg), 4th Group C-10 (carvacrol 10?mg/kg), 5th Group C-20 (carvacrol 20?mg/kg), 6th Group T?+?C-10 (thymol 10?mg/kg?+?carvacrol 10?mg/kg) and 7th Group T?+?C-20 (thymol 20?mg/kg?+?carvacrol 20?mg/kg). The duration of the experiment was 10?weeks for all animals. During the study, sperm quality parameters (motility, concentration, abnormal spermatozoa and live?dead sperm ratio), biochemical parameters [malondialdehyde (MDA), reduced glutathione(GSH), glutathione peroxidase (GSH-Px), catalase (CAT), AST, ALT, GGT, urea and creatinine] were analysed, and histopathological examination was performed. The study results showed that monotherapies of thymol and carvacrol significantly decreased MDA levels in testicles, liver and kidney tissues compared to the control group (p?en_US
dc.identifier.doi10.1080/13813455.2018.1476979
dc.identifier.endpage403en_US
dc.identifier.issn1381-3455
dc.identifier.issn1744-4160
dc.identifier.issue5en_US
dc.identifier.pmid29799283en_US
dc.identifier.scopus2-s2.0-85047411013en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage396en_US
dc.identifier.urihttps://doi.org/10.1080/13813455.2018.1476979
dc.identifier.urihttps://hdl.handle.net/20.500.12483/12569
dc.identifier.volume125en_US
dc.identifier.wosWOS:000488475400002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofArchives of Physiology and Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectThymolen_US
dc.subjectcarvacrolen_US
dc.subjectsperm qualityen_US
dc.subjectoxidative stressen_US
dc.titleEffects of thymol and carvacrol on sperm quality and oxidant/antioxidant balance in ratsen_US
dc.typeArticleen_US

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