Overview of 99mTc-anti-TNF-? scintigraphy: Diagnostic applications
| dc.authorscopusid | 50461202500 | |
| dc.authorscopusid | 54880546000 | |
| dc.authorscopusid | 8665332700 | |
| dc.contributor.author | Elboga, Umut | |
| dc.contributor.author | Kalender, Ebuzer | |
| dc.contributor.author | Yalcin, Hulya | |
| dc.date.accessioned | 2024-09-19T15:41:19Z | |
| dc.date.available | 2024-09-19T15:41:19Z | |
| dc.date.issued | 2014 | |
| dc.department | Hatay Mustafa Kemal Üniversitesi | en_US |
| dc.description.abstract | Tumor necrosis factor alpha (TNF-?) has a role in the pathogenesis of several inflammatory diseases such as rheumatoid arthritis, Crohn's disease, and ulcerative colitis. As TNF-? plays a role in the pathogenesis of different inflammatory diseases, anti-TNF-? agents (monoclonal antibodies [mAbs]) such as infliximab, adalimumab, and certolizumab have been developed and investigated for the treatment of these conditions. In recent years, these mAbs also have been used for diagnosis, monitoring, follow-up of disease activity, and therapy decision-making for inflammatory diseases, especially rheumatoid arthritis, after labeling with 99mTc. However, 99mTc-anti-TNF-? imaging might have severe adverse effects and is expensive. In contrast, scintigraphic imaging before therapy with radiolabeled mAbs may be a cost-effective solution for therapy decisions. © 2014 Elboga et al. | en_US |
| dc.identifier.doi | 10.2147/RMI.S39098 | |
| dc.identifier.endpage | 3 | en_US |
| dc.identifier.issn | 1179-1586 | |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.scopus | 2-s2.0-84892387229 | en_US |
| dc.identifier.scopusquality | Q3 | en_US |
| dc.identifier.startpage | 1 | en_US |
| dc.identifier.uri | https://doi.org/10.2147/RMI.S39098 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12483/14183 | |
| dc.identifier.volume | 7 | en_US |
| dc.indekslendigikaynak | Scopus | en_US |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Reports in Medical Imaging | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Tc tumor necrosis factor-? imaging | en_US |
| dc.subject | mAb | en_US |
| dc.subject | Monoclonal antibodies | en_US |
| dc.subject | Nuclear medicine | en_US |
| dc.title | Overview of 99mTc-anti-TNF-? scintigraphy: Diagnostic applications | en_US |
| dc.type | Review Article | en_US |
