Urodynamic evaluation of acute effects of sildenafil on voiding among males with erectile dysfunction and symptomatic benign prostate

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dc.authoridGuven, Esref Oguz/0000-0003-4919-9383
dc.contributor.authorYalcinkaya, Fatih Rustu
dc.contributor.authorDavarci, Mursel
dc.contributor.authorAkcin, Soner
dc.contributor.authorGokce, Ahmet
dc.contributor.authorGuven, Esref Oguz
dc.contributor.authorInci, Mehmet
dc.contributor.authorBalbay, Mevlana Derya
dc.date.accessioned2024-09-18T20:04:23Z
dc.date.available2024-09-18T20:04:23Z
dc.date.issued2012
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractAim: To evaluate the acute effects of sildenafil citrate on micturition of men with erectile dysfunction and symptomatic benign prostatic hyperplasia using urodynamic parameters. Materials and methods: Between June and December 2009, a total of 50 patients over the age of 40 participated in the study. The patients were admitted to our hospital with erectile dysfunction and moderate to severe lower urinary symptoms with benign prostatic hyperplasia. To examine the sexual function of the participants, we used the IIEF-5 Sexual Health Inventory for Men questionnaire. Patients were randomly divided into 2 groups: a treatment group and a control group. A basal urodynamic evaluation was performed in both groups. After the urodynamic evaluation, 50 mg of sildenafil was given to the patients in the control group and 1 h later a second evaluation was performed. Following the urodynamic evaluation, a placebo was given to the patients in the control group and then a second evaluation was performed after 1 h. Results: A statistically significant increase was seen in maximal flow and average flow (Qmax and Qave) after 1 h in the treatment group. The increase in the control group was not significant. Conclusion: Based on the study findings, we suggest that sildenafil has an effect on micturition in the short term. However, to determine the role of sildenafil in the treatment of BPH/LUTS, further studies with larger patient groups are needed.en_US
dc.identifier.doi10.3906/sag-1009-1119
dc.identifier.endpage956en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-84868710893en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage951en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1009-1119
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8135
dc.identifier.volume42en_US
dc.identifier.wosWOS:000309796300001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBenign prostatic hyperplasiaen_US
dc.subjectlower urinary tract symptomsen_US
dc.subjectphosphodiesterase inhibitorsen_US
dc.subjectsildenafilen_US
dc.subjecturoflowmetryen_US
dc.subjecturodynamicsen_US
dc.titleUrodynamic evaluation of acute effects of sildenafil on voiding among males with erectile dysfunction and symptomatic benign prostateen_US
dc.typeArticleen_US

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