Effect of Caffeic Acid Phenethyl Ester on Plasma Lipid Peroxidation, Antioxidant Status and Nitric Oxide Levels in Incisional Wound Model

Basit Öğe Kaydı
dc.contributor.authorSerarslan, Gamze
dc.contributor.authorAltug, Muhammed Enes
dc.contributor.authorKontas, Tunay
dc.date.accessioned2024-09-18T20:06:21Z
dc.date.available2024-09-18T20:06:21Z
dc.date.issued2007
dc.departmentHatay Mustafa Kemal Ãœniversitesien_US
dc.description.abstractBackground and Design: Wound healing is a complex pathophysiologic process involving interplay of several cellular and biochemical processes. Several natural products have been shown to accelerate the healing process in studies. In this study we aimed to determine the efficacy of caffeic acid phenethyl ester (CAPE), which is an extract of honeybee propolis on wound healing in rats. Materials and Methods: Fourty male Wistar albino rats were divided into two groups as treatment (n=20) and control (n=20) group. A linear full thickness incision was performed on the back of each rat and sutured. After incision, during the study period CAPE was administered to the treatment group and saline was administered to the control group every day. Bloods of 5 animals from each group were collected on the experiment days of 1st, 3rd, 7th and 14th for biochemical analysis. Results: A significant increase in glutathione and nitric oxide levels and a significant decrease in malondialdehyde levels and superoxide dismutase activities in CAPE group were detected when compared to the control group. Conclusion: In the study it determined that CAPE showed an antioxidant effect on wound healing and suppressed lipid peroxidation. In conclusion, because of these properties, CAPE may be useful in wound healing.en_US
dc.identifier.endpage14en_US
dc.identifier.issn1019-214X
dc.identifier.issn1308-6294
dc.identifier.issue1en_US
dc.identifier.startpage11en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8478
dc.identifier.volume41en_US
dc.identifier.wosWOS:000217261000004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherDeri Zuhrevi Hastaliklar Dernegien_US
dc.relation.ispartofTurkderm-Turkish Archives of Dermatology and Venerologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCaffeic acid phenethyl esteren_US
dc.subjectwound healingen_US
dc.subjectantioxidant statusen_US
dc.subjectlipid peroxidationen_US
dc.titleEffect of Caffeic Acid Phenethyl Ester on Plasma Lipid Peroxidation, Antioxidant Status and Nitric Oxide Levels in Incisional Wound Modelen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ N/A ]
Ä°sim:
Tam Metin / Full text
Boyut:
60.01 KB
Biçim:
Adobe Portable Document Format
Ä°ndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu