Is periodontal inflamed surface area associated with serum and salivary levels of IL-1?, visfatin, and omentin-1 in overweight/obese patients?
Yükleniyor...
Dosyalar
Tarih
2022
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer Heidelberg
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objectives The aim of this study was to evaluate the levels of salivary and serum interleukin (IL)-1 beta, visfatin, and omentin-1 in the relationship between periodontal disease and overweight/obesity as well as to reveal the possible role of periodontal inflamed surface area (PISA) in this association. Materials and methods Ninety-six individuals (69 females, 27 males) were divided into 4 groups as systemically healthy (H) and non-periodontitis (HnP, n=23), systemically healthy and periodontitis (HP, n= 24), overweight/obese (O) and nonperiodontitis (OnP, n=25), and overweight/obese and periodontitis (OP, n =24). Periodontal parameters were measured, and PISA was calculated. IL-1 beta, visfatin, and omentin-1 levels in saliva and serum samples were analysed. Results Periodontal parameters deteriorated, salivary and serum IL-1 beta and visfatin levels were increased, and omentin-1 levels were decreased in OnP and OP groups, compared to HnP and HP groups. Salivary and serum IL-1 beta and visfatin levels were increased and omentin-1 levels were decreased in periodontitis groups, compared to HnP and OnP groups. PISA was negatively correlated with salivary omentin-1 and positively correlated with salivary and serum visfatin in H and O groups, whereas a positive relationship was found between PISA and salivary and serum IL-1 beta in H group. Conclusions PISA may be negatively associated with salivary omentin-1, while positively correlated with salivary and serum visfatin in overweight/obese patients.
Açıklama
Anahtar Kelimeler
Adipokines, Obesity, Overweight, Periodontal diseases
Kaynak
Clinical Oral Investigations
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
26
Sayı
8
