Mean platelet volume can predict cerebroyascular events in patients with Sickle Cell Anemia

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dc.contributor.authorCelik, Tanju
dc.contributor.authorUnal, Sule
dc.contributor.authorEkinci, Ozalp
dc.contributor.authorOzer, Cahit
dc.contributor.authorIlhan, Gul
dc.contributor.authorOktay, Gonul
dc.contributor.authorArica, Vefik
dc.date.accessioned2024-09-18T20:54:18Z
dc.date.available2024-09-18T20:54:18Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: The purpose of this study was to determine the impact of mean platelet volume (MPV) on the frequency and severity of vaso-occlusive and cerebrovascular events in patients with sickle cell anemia (SCA). Methods: The 238 cases diagnosed with SCA were evaluated retrospectively with respect to the occurrence of painful crisis for the previous year. The incidence, severity and type of the vaso-occlusive crises of the patients with SCA between March 2010 and March 2011 were recorded. The last MPV values in patients who were free of erythrocyte transfusion for the last three months and who had no current vaso-occlusive crises were evaluated. All the patients were grouped according to the frequency of the crises for the previous year preceding the data collection. Group 1: 1 to 3 crises, Group 2: 4 to 5 and Group 3: 6 or more crises annually. Results: In accordance with the results obtained during the evaluation of the cases diagnosed with sicklecell anemia, MPV value was found to be significantly higher in patients with cerebrovascular events. Also MPV values increased with increasing incidence of the crises (1=0.297) (p=0.001). Conclusion: One of the contributing factors for this clinical heterogeneity may be related to the MPV values in patients with sickle cell anemia. The higher MPV values may be an early predictor of future cerebrovascular events in patients with sickle cell anemia and may require close follow-up and additional measures.en_US
dc.identifier.doi10.12669/pjms.311.4104
dc.identifier.endpage208en_US
dc.identifier.issn1682-024X
dc.identifier.issue1en_US
dc.identifier.pmid25878644en_US
dc.identifier.scopus2-s2.0-84919833317en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage203en_US
dc.identifier.urihttps://doi.org/10.12669/pjms.311.4104
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11730
dc.identifier.volume31en_US
dc.identifier.wosWOS:000349936500041en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherProfessional Medical Publicationsen_US
dc.relation.ispartofPakistan Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPlateletsen_US
dc.subjectSickle cell anemiaen_US
dc.subjectThrombosisen_US
dc.titleMean platelet volume can predict cerebroyascular events in patients with Sickle Cell Anemiaen_US
dc.typeArticleen_US

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