The impact of admission red cell distribution width on long-term cardiovascular events after primary percutaneous intervention: A four-year prospective study

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dc.authoridTanboga, Ibrahim Halil/0000-0003-4546-9227
dc.authoridTURGAY, ISIK/0000-0002-7090-8765
dc.authoriduyarel, huseyin/0000-0001-9931-5456
dc.contributor.authorIsik, Turgay
dc.contributor.authorKurt, Mustafa
dc.contributor.authorTanboga, Ibrahim Halil
dc.contributor.authorAyhan, Erkan
dc.contributor.authorGunaydin, Zeki Yuksel
dc.contributor.authorKaya, Ahmet
dc.contributor.authorUyarel, Huseyin
dc.date.accessioned2024-09-18T20:55:42Z
dc.date.available2024-09-18T20:55:42Z
dc.date.issued2016
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground: Red cell distribution width (RDW) is an indicator of erythrocyte in different size, and its prognostic value has been demonstrated in numerous cardiac and non-cardiac diseases. The purpose of this study was to evaluate the predictive value of RDW on the long-term cardiovascular events in patients undergoing primary percutaneous coronary intervention (PCI). Methods: Ninety-six consecutive patients (mean age 60.6 +/- 12.5 years, 77.1% male) with ST-segment elevation myocardial infarction (STEMI), who were treated with primary PCI, were analyzed prospectively. Baseline RDW and high sensitive C-reactive protein (hs-CRP) were measured. The patients were followed up for major adverse cardiac events (MACE) for up to 48 months after discharge. Results: There were 30 patients with long-term MACE (Group 1) and 66 patients without long-term MACE (Group 2). Age, admission RDW, hs-CRP and creatine kinase-MB levels, heart rate after PCI, previously used angiotensin converting enzyme inhibitor, left anterior descending artery lesion, and electrocardiographic no-reflow were higher in Group 1. Admission hemoglobin levels were lower in Group 1. An RDW level >= 13.85% measured on admission had 80% sensitivity and 64% specificity in predicting long-term MACE on receiver-operating characteristic curve analysis. In multivariate analyses, only admission RDW (HR 5.26, < 95% CI 1.71-16.10; p = 0.004) was an independent predictor of long-term MACE. Conclusions: A high baseline RDW value in patients with STEMI undergoing primary PCI is independently associated with increased risk for long term MACE.en_US
dc.identifier.doi10.5603/CJ.a2015.0080
dc.identifier.endpage288en_US
dc.identifier.issn1897-5593
dc.identifier.issn1898-018X
dc.identifier.issue3en_US
dc.identifier.pmid26711461en_US
dc.identifier.scopus2-s2.0-84978138114en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage281en_US
dc.identifier.urihttps://doi.org/10.5603/CJ.a2015.0080
dc.identifier.urihttps://hdl.handle.net/20.500.12483/12005
dc.identifier.volume23en_US
dc.identifier.wosWOS:000380369500007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVia Medicaen_US
dc.relation.ispartofCardiology Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectred cell distribution widthen_US
dc.subjectST-segment elevation myocardial infarctionen_US
dc.subjectlong-term prognosisen_US
dc.titleThe impact of admission red cell distribution width on long-term cardiovascular events after primary percutaneous intervention: A four-year prospective studyen_US
dc.typeArticleen_US

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