Preventive and Curative Effects of Medical Ozone in Rats Exposed to Experimental Osteomyelitis

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dc.authoridGonenci, Ramazan/0000-0002-4043-2612
dc.contributor.authorGonenci, Ramazan
dc.contributor.authorTabur, Mehmet
dc.contributor.authorOzsoy, Sule Yurdagul
dc.date.accessioned2024-09-18T20:20:05Z
dc.date.available2024-09-18T20:20:05Z
dc.date.issued2017
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractInvestigation of preventive and therapeutic effects of medical ozone in rats with acute osteomyelitis was aimed in this study. Staphylococcus aureus solution was injected intramedullary into right femurs of each animal to form acute osteomyelitis. Preventive Osteomyelitis Group (POG) was taken an ozone session by rectal insufflation daily at a dose of 500 mu g/kg for 15 days with an ozone generator starting a week before microorganism injections, whereas applied nothing to Untreated Osteomyelitis Group (UOG). Treatment Osteomyelitis Group (TOG) was administered the same ozone therapy sessions as POG. But this application was started just after 4 days following the microorganism injection. At the end of the ozone-therapy, two femurs of each animal in 3 groups were excised and examined radiographically, microbiologically and histopathologically. It was found that radiographical differences between UOG and other two osteomyelitis groups were significant, but those between POG and TOG were insignificant. There was not any microbiological reproduction in conventional culture methods. Histopathologically; mild, moderate and severe inflammation findings in the POG, TOG and UOG were observed respectively. Histopathological healing was significant in TOG compared to UOG, and it was significant in POG compared to TOG. Conclusively, it was thought that preventive and curative effects of medical ozone in rats exposed to experimental osteomyelitis had been found. (C) 2017 PVJ. All rights reserveden_US
dc.description.sponsorshipScientific Research Projects Coordination Unit of Mustafa Kemal University, Hatay [1204 Y 0138]en_US
dc.description.sponsorshipThis study was financially supported by Scientific Research Projects Coordination Unit of Mustafa Kemal University, Hatay (Project No: 1204 Y 0138).en_US
dc.identifier.endpage359en_US
dc.identifier.issn0253-8318
dc.identifier.issn2074-7764
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85028308840en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage355en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10046
dc.identifier.volume37en_US
dc.identifier.wosWOS:000408791900021en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherUniv Agriculture, Fac Veterinary Scienceen_US
dc.relation.ispartofPakistan Veterinary Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFemuren_US
dc.subjectMedical Ozoneen_US
dc.subjectOsteomyelitisen_US
dc.subjectRaten_US
dc.subjectRectal Insufflationen_US
dc.subjectTherapyen_US
dc.titlePreventive and Curative Effects of Medical Ozone in Rats Exposed to Experimental Osteomyelitisen_US
dc.typeArticleen_US

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